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Long-Term Outcomes of Surgical Aortic Valve Replacement in Patients with Rheumatoid Arthritis
Background: Patients with rheumatoid arthritis (RA) have increased risk of developing cardiovascular disease and events. Little is, however, known about the influence of RA to the outcomes after surgical aortic valve ...
Epidemiology of Guillain-Barré syndrome in Finland 2004–2014
At total mean incidence of 0.84-1.1/100,000 the occurrence of Guillain-Barre syndrome (GBS) is reported to be low in Finland compared to other Caucasian populations. However, a recent study from Southwestern Finland reported ...
Trends in the surgical management of vesicoureteral reflux in Finland in 2004-2014
<p>Objectives: Previous data on the trends of surgical treatment of vesicoureteral reflux outside USA are<br />scarce. The aim of this study was to clarify the national trends of operative treatment of vesicoureteral<br ...
Occurrence of fatal infective endocarditis: a population-based study in Finland
<div><h4>BACKGROUND: </h4><p>Infective
endocarditis (IE) is a serious mainly bacterial infection associated
with high mortality. Epidemiology of fatal IE is however largely
unknown. We studied occurrence and trends ...
Adult Migraine Hospital Admission Trends in Finland: A Nationwide Registry Study
Population-level data on migraine hospital admission trends are unavailable. Changes in stroke care may have influenced these, since migraine is one of the most common stroke mimics. In this study, all hospital admissions ...
Stroke hospitalization trends of the working-aged in Finland
BackgroundThe age-standardized incidence of stroke has decreased globally but, for reasons unknown, conflicting results have been observed regarding trend in incidence of major stroke subtypes in young adults. We studied ...
Outcome of acute myocardial infarction versus stable coronary artery disease patients treated with coronary bypass surgery
<p>Objective</p><p>To study the long-term outcome differences between acute myocardial infarction (MI) and stable coronary artery disease (CAD) patients treated with coronary artery bypass grafting (CABG). </p><p>Methods ...
Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland
<p>Infective endocarditis (IE) is associated with high mortality. However, data on factors associated with length of stay (LOS) in hospital due to IE are scarce. In addition, long-term mortality of more than 1 year is ...
Long-term outcomes after coronary artery bypass surgery in patients with rheumatoid arthritis
<p><strong>Objective: </strong>To investigate the long-term outcomes of coronary artery bypass grafting surgery (CABG) in patients with rheumatoid arthritis (RA).</p><p><strong>Methods: </strong>Patients with RA (n = 378) were retrospectively compared to patients without RA (n = 7560), all treated with CABG in a multicentre, population-based cohort register study in Finland. The outcomes were studied with propensity score-matching adjustment for baseline features. The median follow-up was 9.7 years.</p><p><strong>Results: </strong>Diagnosis of RA was associated with an increased risk of mortality after CABG compared to patients without RA (HR 1.50; CI 1.28-1.77; p < .0001). In addition, patients with RA were in higher risk of myocardial infarction during the follow-up period (HR 1.61; CI 1.28-2.04; p < .0001). Cumulative rate of repeated revascularization after CABG was 14.4% in RA patients and 12.0% in control patients (p = .060). Duration of RA before CABG (p = .011) and preoperative corticosteroid usage in RA (p = .041) were independently associated with higher mortality after CABG. There were no differences between the study groups in 30-d mortality or in the post-operative usage of cardiovascular medications.</p><p><strong>Conclusions: </strong>RA is independently associated with worse prognosis in coronary artery disease treated with CABG. Preoperative corticosteroid use and longer RA disease duration are additional risk factors for mortality.Key messagesPatients with rheumatoid arthritis (RA) have impaired long-term outcomes after coronary artery bypass surgery (CABG).Glucocorticoid use before CABG and duration of RA are associated with higher mortality.Special attention should be paid in secondary prevention of cardiovascular disease in RA patients after CABG.</p>...