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Aineistot 11-20 / 188
Frailty modeling under a selective sampling protocol: an application to type 1 diabetes related autoantibodies
<p>Abstract<br></p><p>In studies following selective sampling protocols for secondary outcomes, conventional analyses regarding their appearance could provide misguided information. In the large type 1 diabetes prevention ...
INnoVative trial design for testing the Efficacy, Safety and Tolerability of 6-month treatment with incretin-based therapy to prevent type 1 DIAbetes in autoantibody positive participants: A protocol for three parallel double-blind, randomised controlled trials (INVESTDIA)
<p><strong>Aims</strong> beta-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinical type 1 diabetes. We present a protocol of three randomised controlled trials assessing the effects ...
Resting-state networks of the neonate brain identified using independent component analysis
Resting-state functional magnetic resonance imaging (rs-fMRI) has been successfully used to probe the intrinsic functional organization of the brain and to study brain development. Here, we implemented a combination of ...
Sex-specific association between infant caudate volumes and a polygenic risk score for major depressive disorder
Polygenic risk scores for major depressive disorder (PRS-MDD) have been identified in large genome-wide association studies, and recent findings suggest that PRS-MDD might interact with environmental risk factors to shape ...
Performance in Hand Coordination Tasks and Concurrent Functional MRI Findings in 13-Year-Olds Born Very Preterm
<p>Background</p><p>Fine motor and coordination problems are frequently reported among adolescents born preterm. We aimed to assess performance in hand coordination tasks and to compare concurrent brain activation between ...
Respiratory syncytial virus infections in children 0–24 months of age in the community
<p>Objectives: Respiratory syncytial virus (RSV) is a major cause of hospitalization in young children, but there are little data on RSV infections in early childhood in the community. We conducted a prospective population-based ...
Lasten Mycoplasma pneumoniae -infektiot
<p>Mycoplasma pneumoniae on pieni soluseinätön bakteeri, jonka aiheuttamat tautitapaukset painottuvat talvikauteen sekä isompiin epidemioihin. Edellinen laajempi epidemia Pohjois-Euroopassa oli vuosina 2010-2012. Keuhkokuumeen ...
Synnynnäisen hypotyreoosin seulonta vastasyntyneiltä kuiva- ja napaverinäytteistä
LÄHTÖKOHDAT Synnynnäisiä aineenvaihduntasairauksia seulotaan kuivaverinäytteistä koko Suomessa. Synnynnäistä hypotyreoosia seulotaan napaverinäytteistä, toisin kuin muissa länsimaissa.MENETELMÄT Vertasimme synnynnäisen ...
Associations of age and sex with brain volumes and asymmetry in 2–5-week-old infants
<p>Information on normal brain structure and development facilitates the recognition of abnormal developmental trajectories and thus needs to be studied in more detail. We imaged 68 healthy infants aged 2–5 weeks with ...
Newborn amygdalar volumes are associated with maternal prenatal psychological distress in a sex-dependent way
<p>Maternal psychological distress during pregnancy (PPD)<a href="https://www.sciencedirect.com/science/article/pii/S2213158220302175#fn1">1</a> has been associated with changes in offspring amygdalar and hippocampal ...