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Aineistot 201-210 / 224
Influenza vaccine induced antibody responses in relation to evolution of influenza A viruses
(Turun yliopisto, 2022-12-09)
Influenza A viruses (IAVs) cause yearly epidemics and occasionally appearing new pandemics. IAVs are subtyped based on their virion surface glycoproteins haemagglutinin and neuraminidase. Seasonal IA epidemics in humans ...
Bioinformatics of human picornavirus molecular evolution and pathogenesis
(Turun yliopisto, 2022-12-16)
Picornaviruses are a family of small, non-enveloped, positive-sense single-stranded RNA viruses. Together they form group of viruses that in humans cause diseases such as poliomyelitis, encephalitis, hand-foot-and-mouth ...
Potential drug interactions in warfarin users – an observational study focusing on pain medication
(Turun yliopisto, 2023-06-20)
Bleeding is a common and potentially serious adverse drug reaction associated with warfarin therapy. Warfarin undergoes several drug interactions with frequently used pain medications, which themselves are recognized as ...
Exploration of digital biomarkers in chronic low back pain and Parkinson’s disease
(Turun yliopisto, 2023-08-04)
Chronic pain and Parkinson’s disease are illnesses with personal disease progression, symptoms, and the experience of these. The ability to measure and monitor the symptoms by digitally and remotely is still limited. The ...
Developmental aspects of male reproductive health: clinical studies on semen quality, cryptorchidism, and puberty
(Turun yliopisto, 2023-08-11)
Current evidence shows increasing rates of male reproductive disorders, including cryptorchidism, hypospadias, poor semen quality, decreased testosterone level, and testicular cancer. Therefore, studies on the physiology ...
Tools and strategies for RNA-sequencing data analysis
(Turun yliopisto, 2023-08-25)
RNA-Sequencing (RNA-seq) has enabled the in-depth study of the transcriptome, becoming the primary research method in the field of molecular biology. The typical aim of RNA-seq is to quantify and detect differentially ...
Evaluation of digital PET/CT system for myocardial perfusion imaging
(Turun yliopisto, 2023-09-29)
Myocardial perfusion imaging (MPI) with Positron Emission Tomography (PET) allows quantitative measurements of absolute myocardial blood flow (MBF). PET system count-rate capabilities, reconstruction techniques, and other ...
Immunological mechanisms in the pathogenesis of type 1 diabetes
(Turun yliopisto, 2023-06-06)
Type 1 diabetes is a chronic autoimmune disease, in which insulin secreting beta cells in the pancreas are destroyed. The disease pathogenesis can be divided into an asymptomatic preclinical phase and symptomatic disease. ...
Interrelations between microbiota, metabolism and low-grade inflammation with obesity and gestational diabetes mellitus: Means to intervene during pregnancy
(Turun yliopisto, 2023-06-30)
ABSTRACT
Pregnant women with overweight and obesity may exhibit altered circulating lowgrade inflammatory and metabolic profile and gut and vaginal microbiota which may contribute to the development of gestational ...
Convergence of RAS and PP2A activities on chromatin repressor complexes
(Turun yliopisto, 2024-03-22)
Protein Phosphatase 2A (PP2A) is a serine-threonine phosphatase and, through its de-phosphorylation activity, mostly downregulates signaling pathways, while RAS belongs to the family of small GTPase and activates various ...