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Aineistot 1-10 / 16
Aminophenolato complexes of Mo, W and V In catalytic alkene epoxidation and catechol oxidation
(Turun yliopisto, 2021-11-05)
Mo, W and V are found naturally in metalloenzymes such as the Mo/W oxotransferases and the V haloperoxidases (VHPOs). These enzymes catalyze oxidation reactions related to C, N, S metabolism as well as halogenation. Cu and ...
Controlled Decoration of Molecular Spherical Nucleic Acids
(Turun yliopisto, 2022-10-31)
Research on therapeutically effective oligonucleotides (antisense oligonucleotides, ASOs and small interfering RNAs, siRNAs) has grown rapidly during the last decades. Oligonucleotide (ON) therapeutics are nowadays an ...
Highlighting the chemical diversity of plants: modern tools for chemistry education
(Turun yliopisto, 2022-10-28)
The chemical diversity of plants is enormous as plants produce a variety of compounds that play key roles, for instance, in the growth, defence and reproduction of plants. This diversity is not well recognised in chemistry ...
Towards cyclopalladated therapeutic oligonucleotides
(Turun yliopisto, 2021-11-19)
Based on Watson—Crick base pairing principle, therapeutic oligonucleotides bear the potential to either inhibit or alter protein synthesis. Replacing or augmenting Watson—Crick base paring by metal coordination offers a ...
Recognition of single- and double-stranded nucleic acids by covalently mercurated oligonucleotides
(Turun yliopisto, 2021-03-02)
Metal-mediated base pairs have attracted considerable attention during the past decades for their potential in bio- and nanotechnological applications. The introduction of metal ions into DNA or RNA not only stabilizes ...
Semisynthetic preparation of C‑nucleoside 5´-triphosphates as bacterial RNA polymerase substrates
(Turun yliopisto, 2021-12-18)
Interest in natural products as pharmaceutical leads has recently resurfaced due to increasing understanding towards the biosynthesis of natural compounds as well as advancements in methodologies that facilitate the ...
Tuning Photochromic Sodalites across the Visible Spectrum
(Turun yliopisto, 2023-06-16)
Photochromic sodalite, Na8(AlSiO4)6(Cl,S)2, has been a topic of research for almost 100 years, though only recently has a deep understanding of its remarkably fatigueresistant colour change been obtained. Aside from the ...
Oxidative multilayer films and eumelanin analogs for biocompatible supercapacitors
(Turun yliopisto, 2022-12-16)
The future applications of implantable electronic medical devices set heavy requirements for the materials powering the devices. They need to be biocompatible or even biodegradable and have sufficient electrochemical ...
Versatile Ultrathin Films of Conducting Polymers by Vapor Phase Polymerization at Atmospheric Pressure: Synthesis, Process Optimization, and Characterization
(Turun yliopisto, 2022-12-09)
The limitations such as toxicity, brittleness, scarcity, and high cost of currently available materials for energy storage and transparent electrode applications in bendable electronics create a need for green, sustainable, ...
Targeted delivery of molecular spherical nucleic acids
(Turun yliopisto, 2023-09-22)
During the last decades, oligonucleotides (ONs) have emerged as an alternative therapeutic modality for a variety of diseases. They can target disease mechanisms that are considered undruggable by small molecular drugs ...