Hae

In drug development, computer-based methods are constantly evolving as a result of increasing computing power and cumulative costs of generating new pharmaceuticals. With virtual screening (VS), it is possible to screen ...

The earliest academic studies on location-based games (LBGs) were conducted in the early 2000’s, but the recent upsurge in the popularity and success of commercial LBGs has created a need to re-examine the genre in light ...

The study of intrinsic metrics is an interesting area of research in the geometric function theory, which is a subfield of mathematical analysis. The topics of research include quasiregular mappings, conformal capacity and ...

ABSTRACT Receptor tyrosine kinases (RTK) are a family of cell surface receptors consisting of 55 members. RTKs regulate intracellular signaling pathways that control fundamental cellular processes including differentiation, ...

In order to provide high-quality anaesthesia nursing care, competence assessment of nurses is essential. However, in anaesthesia nursing care there has been a lack of psychometrically tested competence assessment scales. ...

ABSTRACT Background: Aortic stenosis (AS) is one the most common heart valve diseases. Symptomatic AS leads to death within a few years if left untreated. For decades, open heart surgery with surgical aortic valve ...

Digital transformation forms an important organisational response to digital technologies and their potential digital disruptions. Especially incumbent organisations face the risk of a diminished market position if they ...

ABSTRACT Nano-sized synthetic drug carriers comprise a valuable addition to oncology armaments, opening new avenues for improved delivery of anticancer therapies. Nanocarriers designed to bind surface receptors of tumor ...

Lyme borreliosis (LB) is the most common tick-borne disease in Europe, caused by spirochete Borrelia burgdorferi sensu lato. Approximately 3–16% of patients with B. burgdorferi infection develop neurological symptoms, ...

ABSTRACT Appendectomy has been the indisputable treatment of acute appendicitis for over a century. Acute appendicitis has been evaluated to always progress to perforation. Current evidence suggests complicated and ...