Aineistot 11-16 / 16
Integration of genome-wide datasets to understand regulation of human T-helper cell differentiation
(Turun yliopisto, 2020-06-05)
T-helper cells are an important part of the immune system and adaptive immunity. Over the course of the immune response, under the influence of various cytokines, T-helper cells differentiate into various subsets each of ...
Immunology of bladder cancer
(Turun yliopisto, 2019-09-20)
Bladder cancer (BC) is a highly prevalent disease with wide variety in outcome. Non-muscle invasive tumors have good prognosis but are prone to recur and, furthermore, have a major risk of progression. Muscle-invasive ...
PLVAP as the gatekeeper of endothelial cell permeability and leukocyte migration
(Turun yliopisto, 2019-10-11)
Endothelial cells (EC) line the lymphatic and vascular vessels of the body, forming a barrier between the lumen and surrounding tissue. ECs actively coordinate the exchange of migrating cells, fluids and molecules thus ...
HLA-A*24 and B*39 alleles in type 1 diabetes risk
(Turun yliopisto, 2020-12-11)
Type 1 diabetes is an autoimmune disease, and it is one of the most common chronic diseases of childhood. An asymptomatic pre-diabetes period preceding the clinical onset is characterized by autoantibodies against pancreatic ...
Immunoregulatory roles of CD73 in lymphatic endothelial and myeloid cells
(Turun yliopisto, 2021-01-29)
The immune system is a fascinating product of the interaction and cooperation of amultitude of cells and tissues. It is thereby able to distinguish between “friend” and “foe” and protect the host from a great variety of ...
Lymphatic endothelial cells regulate traffic in lymph nodes
(Turun yliopisto, 2020-10-23)
Afferent lymphatic vessels transport leukocytes and soluble molecules from the periphery to lymph nodes. These vessels are lined with lymphatic endothelial cells (LEC), which are also present in lymph node sinuses. Lymph ...