Hae
Aineistot 21-30 / 229
Suupatogeenin ulkokalvon rakenteettoman lipoproteiinin ilmentyminen ja osallistuminen DNA:n sisäänottoon
(2022-06-20)
Aggregatibacter actinomycetemcomitans on gram-negatiivinen, opportunistinen suupatogeeni, joka kasvaa hampaan pinnalla biofilminä aiheuttaen kroonista tulehdusta, parodontiittia. A. actinomycetemcomitansin patogeenisuus ...
Monoclonal Expression of Anti-Gelsolin Antibody Libraries in Mammalian Suspension Cells for High-Throughput Screening on Color-Coded Beads
(2022-05-12)
Phage display technology has become a key player in the selection of affinity reagents from antibody libraries. To obtain the best binders from phage combinatorial libraries, affinity screening has been traditionally done ...
Characterization of novel isoform-specific HSP90 inhibitors
(2022-05-16)
90kDa heat shock proteins (HSP90) belong to a family of molecular chaperones involved in the maintenance of dysregulated proteins. Therefore, HSP90 is a promising target in cancer drug research. Classical HSP90 inhibitors ...
Non-genetic rewiring of ERBB signaling in cancer drug tolerance
(2022-05-11)
ERBB receptors are transmembrane receptor tyrosine kinases (RTKs) that are activated by dimerization and intracellular tyrosine phosphorylation upon ligand binding. The ERBB family includes EGFR, ERBB2, ERBB3, and ERBB4 ...
Akkermansia muciniphilan ja Citrobacter rodentiumin vastakkaiset vaikutukset autoimmuunidiabeteksen kehittymiseen NOD-hiirellä
(2022-05-11)
Tyypin 1 diabeteksessa haiman Langerhansin saarekkeiden insuliinia tuottavat betasolut
tuhoutuvat autoimmuunireaktiossa, jolloin glukoositasapainon ylläpito estyy. Antigeeniä
esittelevät solut (APC, antigen presenting ...
Validation of potential CIP2A inhibitors based on computer modeling in triple-negative breast cancer
(2021-07-01)
Cancer is a wide range of diseases that are caused by unchecked multiplication of the cells due to underlying mutations. Rapidly dividing cells may achieve metastasis, which is the stage where cancer cells are able to ...
Designing a quantitative PCR assay for fetal RhD genotyping from maternal plasma derived cell-free fetal DNA
(2022-05-17)
Hemolytic disease of the fetus and newborn (HDFN) is typically caused by maternal alloimmunization against antigens of RhD positive red blood cells. During pregnancy, these anti-RhD antibodies can induce the destruction ...
Photosynthetic characteristics of Pinaceae: From evolution to environmental acclimation
(Turun yliopisto, 2022-06-29)
Boreal evergreen conifers are important for Northern countries and have functioned for centuries as main drivers of the economy. Nowadays, the attention has shifted to the sustainability of the boreal forests, their ...
Stability of phenolics compounds in freeze dried berry products with typically long shelf life
(2022-06-08)
Berries are a potentially rich source of polyphenols, particularly anthocyanins, which may play an important role in the increased risk of chronic diseases. Anthocyanins, which are found primarily in fruits and vegetables, ...
Analysis of volatile aroma-active compounds from a headspace of a novel whiskey glass
(2022-05-31)
In the literature part of this thesis the human olfactory sense is explored. Also, individual differences in the sense of smell are studied. Since the study focuses on whiskey the anesthetic effects of ethanol on the ...