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Aineistot 21-30 / 46
L1-soluadheesiomolekyylin rooli sylkirauhasen myoepiteelikarsinoomassa
(Turun yliopisto, 2016-12-21)
Viimevuosien aikana mielenkiinto syöpää ja sen ennustetekijöitä kohtaa on ollut suuressa kasvussa. Myös L1-soluadheesiomolekyyli (L1CAM tai CD171) on ollut useiden tutkimusryhmien mielenkiinnon kohteena. L1-soluadheesiomolekyylin ...
B Cell Activation and Antibody Responses: The role of vesicle trafficking and Rab GTPases
(Turun yliopisto, 2022-08-12)
B lymphocytes are an important part of the adaptive immune system. As one of their main functions, B cells can recognise specific antigens via their B cell receptor and produce antibodies that help clear infections. In ...
B cell-mediated immunity and signal regulation. The roles of MIM/MTSS1 and IRF4
(Turun yliopisto, 2022-03-11)
B cells constitute an important part of the adaptive immune system and produce antibodies, which protect organism against infectious agents. Recognition of the antigen by the B cell receptor and the following B cell ...
The Process of Digital Pathology and its Application in a Study
(2022-03-23)
Digital pathology saw its advent in the 60’s with the introduction of telepathology and was brought into a brighter spotlight in the late 90’s through the technological breakthrough in histopathological imaging, called ...
Transcriptomic and functional analysis of EWSR1-CREM fusion oncogene in melanoma cell line CHL-1
(2022-03-29)
Fusion genes bearing EWSR1-CREB have been reported in several neoplasms of variating origin, also in melanoma. However, not many have concentrated on the functional role of EWSR1-CREB family fusions in vitro. Less studied ...
Eturauhassyövän kastraatioresistenssiä ennustavat biomerkkiaineet
(Turun yliopisto, 2017-05-22)
Cellular vulnerabilities of glioblastoma
(Turun yliopisto, 2021-10-15)
Glioblastoma (GB) is the most fatal and frequent malignant brain tumor, and it is driven by multiple oncogenic pathways. Despite intensive screening of genomic, transcriptomic, metabolic, and post-translational landscape ...
Pathogenesis of LMNA-related dilated cardiomyopathy
(Turun yliopisto, 2022-03-04)
Dilated cardiomyopathy (DCM) is a progressive myocardial disease that leads to dilatation of cardiac ventricles, reduced contractile force, and a high risk of sudden cardiac death. The second most common gene mutated in ...
Tumor-infiltrating lymphocytes and CD8+ T cells predict survival of triple-negative breast cancer
(2020-04-21)
Triple-negative breast carcinoma is a group of breast cancers that is known for aggressive and unpredictable clinical behavior affecting also younger women. In immunohistochemical staining, triple-negative breast carcinoma ...