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In silico metabolic modelling of Saccharomyces cerevisiae for the overproduction of succinate using OptKnock and OptGene
(Turun yliopisto, 2016-06-08)
Succinate is a naturally occurring metabolite in organism’s cell and is industrially important chemical with various applications in food and pharmaceutical industry. It is also widely used to produce bio-degradable plastics, ...
Exon analysis with CAbase : a novel Carbonic Anhydrases database tool.
(2020-12-21)
The Carbonic Anhydrases are a superfamily of proteins, a type of metalloenzyme that are found ubiquitously throughout the most diverse clades in the tree of life. Since first identified as a catalyst for the reversible ...
“mplementation of bioinformatics pipeline and evaluation of two histone trimethylation data from CUT&RUN analysis of breast cancer cell line SKBR3
(2020-12-14)
Research of chromatin and histone modifications is important for determining phenotypic variability and susceptibility to diseases. Post-translational modifications (PTMs) of histone proteins participate in the regulation ...
Mechanistic exploration of ligand binding to ETB receptor embedded in different membrane environments
(2021-06-04)
Endothelin B (ETB) receptor belongs to a GPCR family, and it consists of seven transmembrane helices connected by three extracellular and intracellular loops. ETB receptor’s main function is vasodilation, thus the receptor ...