Viimeksi syötetyt
Aineistot 12521-12540 / 46619
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Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer
<p>Cancer cells with heterogeneous mutation landscapes and extensive functional redundancy easily develop resistance to monotherapies by emerging activation of compensating or bypassing pathways. To achieve more effective ... -
Kaiken maailman dosentit. Opas dosenttien maailmaan.
Turun yliopistojen dosenttiyhdistyksen julkaisuja.<p>Professorista, tohtorista ja maisterista kaikilla on jonkinlainen<br />mielikuva. Usein aika totuudenmukainenkin. Professori on töissä<br />yliopistolla, tohtori ja maisteri ovat sieltä valmistuneet. Mutta<br />entä ... -
Decidability and universality of quasiminimal subshifts
We introduce quasiminimal subshifts, subshifts having only finitely many subsystems. With N-actions, their theory essentially reduces to the theory of minimal systems, but with Z-actions, the class is much larger. We show ... -
Validation of the short forms of the Pelvic Floor Distress Inventory (PFDI-20), Pelvic Floor Impact Questionnaire (PFIQ-7), and Pelvic Organ Prolapse/ Urinary Incontinence Sexual Questionnaire (PISQ-12) in Finnish
Background: Although several validated generic health-related quality of life instruments exist, disease-specific instruments are important as they are often more sensitive to changes in symptom severity. It is essential ... -
Evaluation of light energy to H2 energy conversion efficiency in thin films of cyanobacteria and green alga under photoautotrophic conditions
<p>Cyanobacteria and green algae harness solar energy to split water and to fix CO2. Under specific conditions, they are capable of photoproduction of molecular hydrogen (H2). This study compares the light-energy-to-hydr ... -
TLR4Polymorphism, Nasopharyngeal Bacterial Colonization, and the Development of Childhood Asthma: A Prospective Birth-Cohort Study in Finnish Children
We aimed to explore the role of TLR4 (rs4986790) polymorphism in the nasopharyngeal (NP) bacterial colonization and its consequent impact on the development of childhood asthma. A semi-quantitative culture of NP swabs was ... -
D-vitamiini ja tyypin 1 diabetes : Seerumin 25-hydroksi-D-vitamiinipitoisuus ja tyypin 1 diabeteksen riski lapsilla
<p>Seerumin D-vitamiinin on todettu olevan yhteydessä joihinkin autoimmuunisairauksiin. Kirjoittaja havaitsi, että seerumin D-vitamiinitasot olivat DIPPtutkimukseen osallistuneilla lapsilla matalia. Suoraa yhteyttä tyypin ... -
Kriittisyys tietojenkäsittelytieteissä
SoPhi<p>Filosofian yksi keskeinen arvo on looginen päättely ja totuuden etsiminen (reason). Filosofia tarkoittaa kreikan kielellä kirjaimellisesti rakkautta viisauteen. Viisaus syntyy vuorovaikutuksessa, joka on myös keskeinen ... -
Elements explaining learning clinical reasoning using simulation games
<p>This article presents the findings on which elements in a game-based simulation affect learning clinical reasoning in nursing education. By using engaging gaming elements in virtual simulations and integrating the ... -
SRG/ART-XC and NuSTAR Observations of the X-Ray pulsar GRO J1008-57 in the Lowest Luminosity State
<p>We report results of the first broadband observation of the transient X-ray pulsar GRO J1008-57 performed in the quiescent state. Observations were conducted quasi-simultaneously with NuSTAR and the Mikhail Pavlinsky ... -
Cross-site analysis of perceived ecosystem service benefits in multifunctional landscapes
<p>Rural development policies in many Organization for Economic Co-operation and Development (OECD) member countries promote sustainable landscape management with the intention of providing multiple ecosystem services (ES). ... -
Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
Aging is an intricate process characterized by multiple hallmarks including stem cell exhaustion, genome instability, epigenome alteration, impaired proteostasis, and cellular senescence. Whereas each of these traits is ... -
Changes in ischemic stroke occurrence following daylight saving time transitions
Background: Circadian rhythm disruption has been associated with increased risk of ischemic stroke ( IS). Daylight saving time (DST) transitions disrupt circadian rhythms and shifts the pattern of diurnal variation in ... -
Tuntemattomat ja tunnetut sotilaat: tekijyys ja dokumentaarisuus jatkosodan taisteluvalokuvissa.
<p>Tutkielmassani olen käsitellyt TK-kuvaajien ja tavallisten rintamamiesten tekijyyttä ja heidän ottamiensa jatkosodan aikaisten kuviensa (kuvat 1–4) dokumentaarisuutta. Sotakuvan muotoutuminen näyttäytyy tutkielmassani ... -
Anticipatory knowledge, epistemic communities and future-oriented innovation practices
<p>The paper aims at linking the ideas of epistemic community, anticipatory knowledge and innovation management. The paper has three core elements. Firstly, it discusses the idea of anticipatory knowledge in the context ... -
Structural and metamorphic evolution of the Turku migmatite complex, southwestern Finland
<p> The Turku migmatite complex in southwestern Finland is a representative area for the type of tectonic and metamorphic evolution seen within the Palaeoproterozoic Svecofennian Orogen in southern Finland. The orogeny ... -
The importance of the learning process in ST analysis interpretation and its impact in improving clinical and neonatal outcomes
<p>BACKGROUND: Intrapartum fetal heart rate monitoring was introduced with the goal to reduce fetal hypoxia and deaths. However, continuous fetal heart rate monitoring has been shown to have a high sensitivity but also a ...
