Viimeksi syötetyt
Aineistot 22401-22420 / 45877
-
BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity
Benzofuroxan is an interesting ring system, which has shown a wide spectrum of biological responses against tumor cell lines. We investigated, herein, the antitumor effects of benzofuroxan derivatives (BFDs) in vitro and ... -
Kristinuskoon viittaaminen eduskunnan täysistuntopuheenvuoroissa 1999–2019
<p>In this article, I analyze the speeches held in the Parliament of Finland between 1999 and 2019 that referenced Christianity (n = 622). I pay special attention to the ways in which the different parties construct Finnish ... -
Immigrants’ use of healthcare in their country of origin: the role of social integration, discrimination and parallel use of healthcare systems.
<h3>Aims</h3><p>The objective of this study was to elucidate the utilisation of Russian health care by immigrants of Russian origin living in Finland (cross-border health care). The study examined the association of ... -
Actualized lower body contouring surgery after bariatric surgery - a nationwide register-based study
Massive weight loss might lead to excess skin folds causing functional, physical, and psychosocial discomfort. Following bariatric procedures, an increasing number of patients are seeking lower body contouring surgery ... -
The Erosion of Borderless Norden? Practices and Discourses on Nordic Border Restrictions in Finland and Sweden during the Covid-19 Pandemic
Nordic countries are part of the borderless Schengen Area, but free movement in the Nordic countries, or Norden, dates back even further: no border controls or restrictions on workers' movements have existed since the entry ... -
Genetic association study of childhood aggression across raters, instruments, and age
<p>Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association metaanalysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages ... -
Sindbis virus outbreak and evidence for geographical expansion in Finland, 2021
Sindbis virus (SINV) caused a large outbreak in Finland in 2021 with 566 laboratory-confirmed human cases and a notable geographical expansion. Compared with the last large outbreak in 2002, incidence was higher in several ... -
A specific hybridisation internalisation probe (SHIP) enables precise live-cell and super-resolution imaging of internalized cargo
Facilitated by the advancements in microscopy, our understanding of the complexity of intracellular vesicle traffic has dramatically increased in recent years. However, distinguishing between plasma membrane-bound or ... -
Performance Assessment of Reference Modelling Methods for Defect Evaluation in Asphalt Concrete
The deterioration of road conditions and increasing repair deficits pose challenges for the maintenance of reliable road infrastructure, and thus threaten, for example, safety and the fluent flow of traffic. Improved and ... -
Performance of Moral Accountability and the Ethics of Satire in Stand-Up Comedy
<p>This paper explores an approach to satire in stand-up comedy at the intersection of emotion and ethics. It is suggested that morally charged emotional language is particularly situated in stand-up due to the ... -
Impairment of peroxisomal APX and CAT activities increases protection of photosynthesis under oxidative stress
<p>Retrograde signalling pathways that are triggered by changes in cellular redox homeostasis remain poorly understood.</p><p> </p><p></p><p>Transformed rice plants that are deficient in peroxisomal ascorbate peroxidase ... -
‘Even with all this, I could not live without kinkiness’. Kinky Understandings of Everyday Life.
<p>In this article, we discuss the relationship of kink and everyday life and ask how kinky-identified individuals negotiate the relationship between kinkiness and everyday life in a society that stigmatises kink. We address ... -
Plasma lipid alterations in young adults with psychotic experiences: A study from the Avon Longitudinal Study of Parents and Children cohort
<p>Background<br></p><p>Psychotic experiences (PEs) are associated with an increased risk of future psychotic and non-psychotic mental disorders. The identification of biomarkers of PEs may provide insights regarding the ... -
Empirical multi-wavelength prediction method for very high energy gamma-ray emitting BL Lacertae objects
Aim: We have collected the most complete multi-wavelength (6.0-6.0 x 10(18) cm) dataset of very high energy (VHE) gamma-ray emitting (TeV) BL Lacs, which are the most numerous extragalactic VHE sources. Using significant ... -
Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene
Bronchopulmonary dysplasia (BPD), the main consequence of prematurity, has a significant heritability, but little is known about predisposing genes. The aim of this study was to identify gene loci predisposing infants to ... -
Effect of High-Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long-lasting Inhibition of CYP2C19
In vitro, esomeprazole is a time-dependent inhibitor of CYP2C19. Additionally, racemic omeprazole induces CYP1A2 and omeprazole and its metabolites inhibit CYP3A4in vitro. In this 5-phase study, 10 healthy volunteers ...
