Hae

Background: Prostate cancer (PCa) is the most commonly diagnosed cancer and second leading cause of cancer-related deaths for men in Western countries. The advanced form of the disease is life-threatening with few options ...

The main goal of this thesis work has been to develop tools to recover hidden structures, latent variables, or latent subspaces for multivariate and dependent time series data. The secondary goal has been to write ...

This thesis is comprised of four articles in multiplicative number theory, a subfield of analytic number theory that studies questions related to prime numbers and multiplicative functions. A central principle in multiplicative ...

The research area of this thesis is Geometric Function Theory, which is a subfield of mathematical analysis. The thesis consists of four published papers. Prepublication versions of these papers are available on the www-pages ...

Construction of multiple sequence alignments is a fundamental task in Bioinformatics. Multiple sequence alignments are used as a prerequisite in many Bioinformatics methods, and subsequently the quality of such methods can ...

Ecological specialization in resource utilization has various facades ranging from nutritional resources via host use of parasites or phytophagous insects to local adaptation in different habitats. Therefore, the evolution ...

The purpose of this thesis is twofold. The first and major part is devoted to sensitivity analysis of various discrete optimization problems while the second part addresses methods applied for calculating measures of ...

Almost every problem of design, planning and management in the technical and organizational systems has several conflicting goals or interests. Nowadays, multicriteria decision models represent a rapidly developing area ...

Organotypic cancer cell cultures combined with modern imaging technology have greatly expanded the possibilities of in vitro cancer research and drug development. In fact, imaging and subsequent image analyses have become ...

In 1859, Charles Darwin published his theory of evolution by natural selection, the process occurring based on fitness benefits and fitness costs at the individual level. Traditionally, evolution has been investigated by ...