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Distribution and oxidative activities of phenolic compounds in the plant kingdom
(Turun yliopisto, 2020-12-08)
Plant phenolics have been studied for decades because of their role as chemodefensive compounds against herbivores and pathogens, and their assumed health benefits to humans. One of their proposed modes of actions is ...
The peptide-break technology : a novel approach for protein post-translational modification assays in drug discovery
(Turun yliopisto, 2019-03-15)
The work presented in this thesis describes the development of a universal platform for the biochemical detection of protein post-translational modifications (PTM) using the quenching resonance energy transfer (QRET) ...
Energy transfer in luminescent lanthanoid chelates
(Turun yliopisto, 2020-05-29)
Luminescent lanthanoid complexes are widely utilized, especially in the medical diagnostics. The complexes have been much studied and ligands with high quantum efficiency have been developed for different lanthanoid ions ...
[18F]F2 – New production methods and applications
(Turun yliopisto, 2018-12-19)
Fluorine-18 is a positron emitting radioisotope. It has a half-life of 109.8 min, a simple decay profile and low positron energy as a result of which properties fluorine-18 is an excellent candidate for use in the production ...
Recognition of double-helical DNA and RNA by modified triplex-forming oligonucleotides and peptide nucleic acids
(Turun yliopisto, 2019-10-11)
Triplex-forming oligonucleotides (TFOs) have received considerable interest because of their ability to recognize double-helical DNA and RNA sequenceselectively. Sequence-selective binding to double-helical DNA would enable ...
Electrochemical fabrication of nanocomposites towards sustainable energy applications
(Turun yliopisto, 2019-03-08)
In the fight against climate change, effective energy storage applications are required to efficiently store the energy of renewable sources. Supercapacitors are one of the energy storage applications under vigorous research ...
Radiosynthesis of [¹⁸F]F-DPA with various molar activities for the imaging of neuroinflammation
(Turun yliopisto, 2019-06-14)
The use of radioisotopes as a means to non-invasively look into living subjects influenced both diagnostic and therapeutic medicine in the past century. Nowadays positron emission tomography (PET), employing short-lived ...
Synthetic hackmanites and their optical properties – from theory to applications
(Turun yliopisto, 2019-05-17)
Synthetic hackmanite is a material that resembles the natural mineral, hackmanite. The structure of hackmanite, Na8Al6Si6O24(Cl,S)2, together with its simple preparation with solid state synthesis enables the doping of ...
Studies on cationic polythiophenes with hydrogen-bonding donor capabilities
(Turun yliopisto, 2019-11-08)
This project focuses on cationic isothiouronium polythiophenes (CITs), a particular type of conjugated polyelectrolytes (CPEs). In general, CPEs combine a pi-conjugated polymer backbone with pendant ionic groups, which ...
Structure elucidation and ruminant-related bioactivities of purified proanthocyanidins
(Turun yliopisto, 2020-12-15)
In this thesis work, a group of natural oligomers and polymers called proanthocyanidins was studied via multiple chemical approaches. At first, the proanthocyanidins were purified from eleven Finnish plant species with a ...