Hae
Aineistot 3561-3570 / 3867
Novel prognostic factors for advanced melanoma and localized renal cell carcinoma
(Turun yliopisto, 2022-01-28)
This study aimed to evaluate prognostic and predictive factors in melanoma and renal cell carcinoma to tailor optimal treatment and follow-up for cancer patients.
Chemotherapy was the standard treatment for advanced ...
Cohort studies of influenza vaccine effectiveness: Based on Finnish register data
(Turun yliopisto, 2021-10-08)
This thesis is motivated by the Finnish policy of estimating inuenza vaccine effectiveness, i.e., the vaccine-attributable reduction in inuenza incidence, each season from medical and demographic register data. It presents ...
The Integrin Tail: A Tale of Cell Motility and Division
(Annales Universitatis Turkuensis D 928Turun yliopisto, 2010-11-12)
Integrin transmembrane receptor functions are regulated by adaptor molecules binding to their alpha and beta subunit intracellular domains, or tails, thus affecting integrin traffic and adhesion during e.g. cell motility. ...
Identification and characterisation of a novel adhesin of Streptococcus suis and its use as a target of adhesion inhibition and bacterial detection
(Annales Universitatis Turkuensis D 1042Turun yliopisto, 2012-11-16)
Streptococcus suis is an important pig pathogen but it is also zoonotic, i.e. capable of causing
diseases in humans. Human S. suis infections are quite uncommon but potentially life-threatening
and the pathogen is an ...
Interactions between Human Mesenchymal Stem Cells and Circulating Mononuclear Cells in Bone Regeneration
(Annales Universitatis Turkuensis D 1250Turun yliopisto, 2016-10-12)
Despite the regenerative actions of bone marrow mesenchymal stem cells (BM-MSCs) and optimal reduction, ossification is delayed in almost 10% of all fractures, requiring surgical intervention. The gold standard for treating ...
Detection of the Vulnerable Atherosclerotic Plaque. Pre-Clinical Evaluation of Novel PET Imaging Probes With Experimental Models
(Annales Universitatis Turkuensis D 1030Turun yliopisto, 2012-10-05)
Atherosclerosis is a life-long vascular inflammatory disease and the leading cause of
death in Finland and in other western societies. The development of atherosclerotic
plaques is progressive and they form when lipids ...
Young Registered Nurses’ Intent to Leave the Profession in Finland - A Mixed-Method Study
(Annales Universitatis Turkuensis D 1107Turun yliopisto, 2014-04-11)
The purpose of this study was to examine and expand understanding concerning young Finnish registered nurses (RN) with an intention to leave the profession and the related variables, specifically when that intention has ...
Alpha- and gamma-melanocyte stimulating hormones in obesity. A study of the key central areas of metabolic regulation
(Annales Universitatis Turkuensis D 1128Turun yliopisto, 2014-09-19)
The melanocortin system is an important regulator of feeding, energy metabolism,and cardiovascular function and it consists of the pro-opiomelanocortin (POMC) derived melanocyte stimulating hormones (α-, β- and γ-MSH) and ...
Clinical studies on testicular growth and descent
(Turun yliopisto, 2018-02-02)
Recent population-based cohort studies indicate that semen quality is declining and simultaneously the incidence of testicular germ-cell cancer is increasing globally. A failure of testicular descent i.e. cryptorchidism ...
Novel Imaging Approaches for the Detection of Hemodynamically Significant Coronary Artery Disease: Quantitative Flow Ratio and Artificial Intelligence-Based Ischemia Algorithm
(Turun yliopisto, 2024-06-08)
ABSTRACT
In coronary artery disease (CAD), the decision on revascularization is based on the hemodynamic significance of stenoses. However, this cannot directly be determined from the first-line anatomical imaging methods ...