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Aineistot 31-40 / 44
Ultrasensitiivisen HIV-1 p24 ELISA-määritysmenetelmän karakterisointi veritäplillä
(Turun yliopisto, 2017-04-04)
The Role of maternal prenatal distress in the development and functioning of the infant cortisol stress response
(Turun yliopisto, 2022-01-21)
The adrenal cortex secretes cortisol during stressful situations to regulate stress reactions of several other systems, such as the immune system, to enhance coping and survival. An altered cortisol stress responsiveness ...
Disruption of Clever-1 for Novel Anticancer Immunotherapy
(Turun yliopisto, 2016-11-22)
The progression of cancer is dependent on the quality of the immune response elicited by the tumour. Typically, proinflammatory immune responses restrain and anti-inflammatory immune responses promote the progression of ...
Cavity-based negative images in molecular docking
(Turun yliopisto, 2021-10-01)
In drug development, computer-based methods are constantly evolving as a result of increasing computing power and cumulative costs of generating new pharmaceuticals. With virtual screening (VS), it is possible to screen ...
Combination of Metformin and Inorganic Nitrate: Effects on Metabolic Disease and Lactic Acidosis
(Turun yliopisto, 2017-08-08)
Nitric oxide (NO) is a diatomic gaseous molecule generated in our bodies by enzymes known as NO synthases. More recently another pathway for generation of NO has been delineated in which dietary or endogenous inorganic ...
Identifying candidate markers associated with the early progression of Alzheimer’s disease pathology in APPPS1-21 mouse model
(Turun yliopisto, 2017-08-08)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease manifested clinically as memory loss in the early stages of the disease and cognitive dysfunction at later stages. These symptoms can be due to synaptic ...
Combination of Metformin and Inorganic Nitrate: Effects on Metabolic Disease and Lactic Acidosis
(Turun yliopisto, 2017-08-10)
Nitric oxide (NO) is a diatomic gaseous molecule generated in our bodies by enzymes known as NO synthases. More recently another pathway for generation of NO has been delineated in which dietary or endogenous inorganic ...
AA29504 Modulation of Radioligand Binding to αβγ2 and αβδ GABAA Receptors
(Turun yliopisto, 2017-04-05)
The effects of transgenic melanocortin overexpression in atherosclerotic mice
(Turun yliopisto, 2016-12-14)
Atherosclerosis is a chronic inflammatory disease of the arteries and a common cause of death worldwide. The disease is initiated by endothelial dysfunction that allows the transport of leukocytes and ...
The Role of Beta Subunit Variant on the Properties of Delta-Containing Extrasynaptic GABAA Receptors
(Turun yliopisto, 2017-08-10)
Muscimol, a psychoactive constituent of Amanita muscaria, activates all GABAA receptor subtypes with exceptionally high affinity to αβδ. This is explained by δ subunit role on muscimol extremely slow dissociation from these ...