Hae

The progression of cancer is dependent on the quality of the immune response elicited by the tumour. Typically, proinflammatory immune responses restrain and anti-inflammatory immune responses promote the progression of ...

Nitric oxide (NO) is a diatomic gaseous molecule generated in our bodies by enzymes known as NO synthases. More recently another pathway for generation of NO has been delineated in which dietary or endogenous inorganic ...

Alzheimer’s disease (AD) is a progressive neurodegenerative disease manifested clinically as memory loss in the early stages of the disease and cognitive dysfunction at later stages. These symptoms can be due to synaptic ...

Nitric oxide (NO) is a diatomic gaseous molecule generated in our bodies by enzymes known as NO synthases. More recently another pathway for generation of NO has been delineated in which dietary or endogenous inorganic ...

Atherosclerosis is a chronic inflammatory disease of the arteries and a common cause of death worldwide. The disease is initiated by endothelial dysfunction that allows the transport of leukocytes and ...

Muscimol, a psychoactive constituent of Amanita muscaria, activates all GABAA receptor subtypes with exceptionally high affinity to αβδ. This is explained by δ subunit role on muscimol extremely slow dissociation from these ...

Kliininen lääketutkimus on ihmiseen kohdistuva interventiotutkimus, jonka tavoitteena on selvittää lääkeaineiden farmakodynaamisia sekä farmakokineettisiä ominaisuuksia ihmiselimistössä. Tutkittavien rekrytointi ...

The melanocortin system comprises of melanocortin peptides; α-, β- and γ- melanocortin stimulating hormones (MSH) and adrenocorticotropic hormone (ACTH) derived from the proteolytic degradation ...

Telomeerit suojaavat kromosomien päitä lopetusjaksoina, jotka lyhenevät jokaisessa solunjakautumisessa. Kun telomeerit ovat lyhentyneet kriittisesti, solu ei voi enää jakautua. Telomeraasi on ribonukleoproteiinientsyymi, ...