Viimeksi syötetyt
Aineistot 22721-22740 / 46619
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A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo
Short peptide sequences from complementarity-determining regions (CDRs) of different immunoglobulins may exert anti-infective, immunomodulatory and antitumor activities regardless of the specificity of the original monoclonal ... -
The hidden admission agendas in Finnish primary teacher education in the 1990s, 2000s and 2010s
<p>Applicants’ suitability for the teaching profession has been underlined in admissions to Finnish primary teacher education. Nevertheless, hidden agendas beyond teacher competence frameworks and attribute definitions ... -
Food for thought: How cell adhesion coordinates nutrient sensing
Cell adhesion controls cell survival and proliferation via multiple mechanisms. Rabanal-Ruiz et al. (2021. J. Cell Biol. https://doi. org/10.1083/jcb.202004010) demonstrate that focal adhesions are key signaling hubs for ... -
The Blanco DECam bulge survey. I. The survey description and early results
The Blanco Dark Energy Camera (DECam) Bulge survey is a Vera Rubin Observatory (LSST) pathfinder imaging survey, spanning similar to 200 deg(2) of the Southern Galactic bulge, -2 degrees < b < -13 degrees and -11 degrees ... -
The invasive herb Lupinus polyphyllus can reduce plant species richness independently of local invasion age
The ecological impacts of invasive species may change or accumulate with time since local invasion, potentially inducing further changes in communities and the abiotic environment. Yet, time since invasion is rarely ... -
Material Talk – The Arctic Continental Shelf in the Law of the Sea Policy Discussion of the United States
The Yearbook of Polar LawThe legal status of a large area of the Arctic seafloor is currently being redefined as the rapid melting of polar ice is enabling the exploitation and study of resource-rich underwater areas. The United Nations Convention ... -
Yllätyksiin täytyy tottua – energiajärjestelmän murroksen seurauksia energiaturvallisuudelle.
<p>Tulevaisuuden uusiutuvilla energiajärjestelmillä voi olla yllättävä seuraus: yhteiskuntien kompleksisuuden lisääntyminen. Toisin kuin usein ajatellaan, energiamurros uusiutuviin energialähteisiin lisää globaalisti ... -
Enrichment of Pachytene Spermatocytes and Spermatids from Mouse Testes Using Standard Laboratory Equipment
To characterize each step of spermatogenesis, researchers must separate different subpopulations of germ cells from testes. However, isolating discrete populations is challenging, because the adult testis contains a complex ... -
Synthesis of 3',5'-Cyclic Phosphate and Thiophosphate Esters of 2'-C-Methyl Ribonucleosides
2'-C-Methylnucleosides are known to exhibit antiviral activity against Hepatitis C virus. Since the inhibitory activity depends on their intracellular conversion to 5'-triphosphates, dosing as appropriately protected ... -
Seam Tracking with Adaptive Image Capture for Fine-tuning of a High Power Laser Welding Process
<p> This paper presents the development of methods for real-time fine-tuning of a high power laser welding process of thick steel by using a compact smart camera system. When performing welding in butt-joint configuration, ... -
Antecedents and consequences of the perceived usefulness of smoking cessation online health communities
<div><h3>Purpose</h3><p>An empirical study investigated the antecedents to perceived usefulness (PU) and its consequences in the context of smoking cessation online health communities (OHCs).</p></div><div><h3>Design/met ... -
Exploring the embodied subtleties of collaborative creativity: What organisations can learn from dance
<p>This study illustrates the value of embodied subtleties in the process of collaborative creativity. Drawing on a sensory ethnography of two dance productions, we illustrate the fine-grained ways in which professional ... -
A novel automated tower graph based ECG signal classification method with hexadecimal local adaptive binary pattern and deep learning
<p>Electrocardiography (ECG) signal recognition is one of the popular research topics for machine learning. In this paper, a novel transformation called tower graph transformation is proposed to classify ECG signals with ... -
Ten-year experience with transcatheter and surgical aortic valve replacement in Finland
<p>Aim: We investigated the outcomes of transcatheter (TAVR) and surgical aortic valve replacement (SAVR) in Finland during the last decade. <br></p><p>Methods: The nationwide FinnValve registry included data from 6463 ... -
Olisiko hydromorfonista oksikodonin haastajaksi?
<p>Hydromorfoni on lähes sata vuotta vanha opioidi, jonka käyttö maassamme on ollut melko vähäistä. Nyt hydromorfonista on tullut Suomen markkinoille myös parenteraalinen valmiste. Finnanest pyysi dosentti Teijo Saarta ... -
Living on the edge: Gamete release and subsequent fertilisation in Fucus vesiculosus (Phaeophyceae) are weakened by climate change–forced hyposaline conditions
<p>Populations at range margins of marine organisms are at the front line of climate-induced changes in abiotic factors and are thus particularly susceptible. Especially, macroalgae that are externally reproducing rely on ... -
Bruneian Suicidal behaviors among school attending adolescents: A nationwide cross sectional study
<p>Background: It is aimed to determine the prevalence of suicidal behaviors regarding to epidemiological and psychosocial characteristics among Bruneian school-student adolescents.<br />Methods: The cross-sectional study ... -
Long term effects on technology enhanced learning: The use of weekly digital lessons in mathematics
<p> </p><div> <div> <div> <p>In this study we investigate the effects of long-term technology enhanced learning (TEL) in mathematics learning performance and fluency, and how technology enhanced ...
