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Towards improved characterization of prostate cancer using magnetic resonance imaging and positron emission tomography
(Turun yliopisto, 2017-08-29)
Approximately every seventh man will be diagnosed with prostate cancer during his life. Prostate cancer has a wide range of aggressiveness ranging from indolent to lethal disease. Accurate characterisation of prostate ...
Splanchnic Metabolism and Blood Flow In Man. PET Studies with Reference to Obesity and Diabetes
(Turun yliopisto, 2016-12-16)
Splanchnic region comprises the interaction of multiple organs, hormones and neural factors and is a critical regulator of glucose homeostasis during both postabsorptive and absorptive states. While ...
Superoxide dismutase 3-mediated cell survival and proliferation
(Annales Universitatis Turkuensis D 1001Turun yliopisto, 2012-01-20)
This dissertation studies the signaling events mediated by the extracellular superoxide dismutase (SOD3). SOD3 is an antioxidant enzyme which converts the harmful superoxide into hydrogen peroxide. Overproduction of these ...
Työn fyysinen ja psyykkinen kuormittavuus vanhustenhoidossa - seurantatutkimus ergonomisen kehittämistyön tuloksista
(Annales Universitatis Turkuensis C 391Turun yliopisto, 2014-10-10)
Tutkimuksen tarkoituksena oli analysoida vanhusten ympärivuorokautisen hoidon yksiköissä työskentelevien työntekijöiden työn fyysistä ja psyykkistä kuormittavuutta ja työhön liittyviä fyysisiä riskejä. Lisäksi haluttiin ...
Prediction of neurodevelopment and neuromotor trajectories in very preterm born children up to 11 years of age: PIPARI Study
(Annales Universitatis Turkuensis D 1226Turun yliopisto, 2016-05-20)
Very preterm birth is a risk for brain injury and abnormal neurodevelopment. While the incidence of cerebral palsy has decreased due to advances in perinatal and neonatal care, the rate of less severe neuromotor problems ...
Primary and Revision Hip Replacement. A University Hospital Database and Registry Study
(Annales Universitatis Turkuensis D 1125Turun yliopisto, 2014-09-19)
Large-headed total hip arthroplasty (THA) and hip resurfacing arthroplasty (HRA) with metal-on-metal (MoM) bearings became popular during the last decade. Recently, it has become evident that the large-head MoM hip implants ...
Mitochondrial disease in Southwestern Finland. Population-based molecular genetic and clinical studies
(Annales Universitatis Turkuensis D 1021Turun yliopisto, 2012-08-17)
Mitochondria are present in all eukaryotic cells. They enable these cells utilize oxygen
in the production of adenosine triphosphate in the oxidative phosphorylation system,
the mitochondrial respiratory chain. The concept ...
Imaging of Tumour Microenvironment for the Planning of Oncological Therapies Using Positron Emission Tomography
(Annales Universitatis Turkuensis D 1051Turun yliopisto, 2013-01-25)
Tumour cells differ from normal tissue cells in several important ways. These
differences, like for example changed energy metabolism, result in altered
microenvironment of malignant tumours. Non-invasive imaging of ...
Prenatal and perinatal risk factors for bipolar disorder
(Annales Universitatis Turkuensis D 1176Turun yliopisto, 2015-05-28)
Bipolar disorder (BPD) is a severe mental disorder associated with considerable morbidity and mortality. Prenatal insults have been shown to be associated with later development of mental disorders and there is a growing ...
Quantitative Magnetic Resonance Imaging of the Liver and Heart In Iron Overload
(Turun yliopisto, 2014-12-12)
Systemic iron overload (IO) is considered a principal determinant in the clinical outcome of different forms of IO and in allogeneic hematopoietic stem cell transplantation (alloSCT). However, indirect markers for iron do ...