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After a preterm birth, the optimal growth environment in utero is replaced by a completely different, often rather stressful environment in the neonatal intensive care unit (NICU), which could potentially be harmful to the ...

In addition to individual and social factors, many environmental factors can modify physical activity. However, few studies have focused on older age groups. The aims of this dissertation were to examine the contexts in ...

Background: Metabolic bariatric surgery (MBS) is the most effective treatment of severe obesity, a global epidemic associated with multiple comorbidities. MBS may result in type 2 diabetes (T2D) remission. The Individualized ...

The prostate-specific antigen (PSA) is the main biomarker for diagnosis and treatment response monitoring in prostate cancer (PCa). In the first part of this thesis, we investigated the prognostic value of ultrasensitive ...

Neuroinflammation (NI) is a key player in neurodegenerative diseases, such as multiple sclerosis (MS). Magnetic resonance imaging is the gold standard imaging method for diagnosis of MS, however, better diagnostic tools ...

Spondylolysis is the most common cause of low back pain in adolescents, explaining up to 47% of low back pain in young athletes. It is a stress fracture in one or both of the pars interarticularis of the vertebra, most ...

Allergic diseases, including food allergies, atopic eczema, wheezing, asthma and allergic rhinitis, have a complex and multifactorial pathogenesis. The most important risk factor for atopic diseases in children is genetic ...

During the few past decades the lifespan of persons with intellectual disability has increased significantly, though only little is known how ageing affects cognition and health of intellectually disabled persons. In ...

While hypertension has been linked to various modifiable and fixed risk factors, the exact mechanisms behind blood pressure (BP) regulation and hypertension onset remain elusive. The rapid development in scientific branches ...

The health benefits of exercise have been known as early as the 5th century. Since then many studies have corroborated these benefits involving both animal and human subjects. But still, the scientific community is uncertain ...