Aineistot 31-40 / 53
Solid-Phase Organic Synthesis: Bicyclic Peptides and Purine-Derived Small Molecules
(Turun yliopistoAnnales Universitatis Turkuensis A I 474, 2013-11-15)
Brown algal phlorotannins: Improving and applying chemical methods
(Turun yliopistoAnnales Universitatis Turkuensis AI 381, 2008-02-22)
Phlorotannins are the least studied group of tannins and are found only in brown algae. Hitherto the roles of phlorotannins, e.g. in plant-herbivore interactions, have been studied by quantifying the total contents of the ...
The Significance of Hydrogen Bonding Interactions in the Cleavage of RNA
(Turun yliopistoAnnales Universitatis Turkuensis A I 418, 2011-05-20)
RNA is essential for all living organisms. It has important roles in protein synthesis, controlling gene expression as well as catalyzing biological reactions. Chemically RNA is a very stable molecule, although in biological ...
Synthesis of Short Oligonucleotides on a Soluble Support by the Phosphoramidite Method
(Turun yliopistoAnnales Universitatis Turkuensis A I 521, 2015-09-04)
In the last decades, the chemical synthesis of short oligonucleotides has become an important aspect of study due to the discovery of new functions for nucleic acids such as antisense oligonucleotides (ASOs), aptamers, ...
Prodrug strategies of antiviral nucleotides: Studies on enzymatically and thermally removable phosphate protecting groups
(Turun yliopistoTurun yliopiston julkaisuja - Annales Universitatis Turkuensis. Sarja - ser. AI osa - tom. 522, 2015-09-18)
Antiviral nucleosides are compounds that are used against viruses, such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). To act as therapeutic agent, the antiviral nucleoside needs to be phosphorylated ...
Lanthanide doped NaYF4 up-conversion luminescence materials
(Turun yliopistoAnnales Universitatis Turkuensis A I 550, 2016-12-14)
The thesis includes literature and experimental parts. The first part introduces the reader to the topic while the later part contains synthesis and characterization details, results and publications. Up-conversion (UPC) ...
Understanding the bioactivity of plant tannins: developments in analysis methods and structure-activity studies
(Turun yliopistoAnnales Universitatis Turkuensis A I 540, 2016-06-17)
Tannins, typically segregated into two major groups, the hydrolyzable tannins (HTs) and the proanthocyanidins (PAs), are plant polyphenolic secondary metabolites found throughout the plant kingdom. On one hand, tannins may ...
Flavonoids and other phenolic compounds: characterization and interactions with lepidopteran and sawfly larvae
(Turun yliopistoAnnales Universitatis Turkuensis A I 496, 2014-11-14)
This thesis focuses on flavonoids, a subgroup of phenolic compounds produced by plants, and how they affect the herbivorous larvae of lepidopterans and sawflies. The first part of the literature review examines different ...
Nucleotides as Antiviral Compounds. On the Feasibility of an Esterase-dependent Prodrug Strategy for 2-5A
(Turun yliopistoAnnales Universitatis Turkuensis A I 516, 2015-06-05)
Nukleotidien ja oligonukleotidien analogeilla on merkittävä rooli virusten aiheuttamien tautien hoidossa. Tämän kaltaiset yhdisteet voivat estää spesifisesti virusten proteiineja tai aktivoida luontaista immuunijärjestelmää, ...
Recognition of nucleic acids by metal ion complexes
(Turun yliopistoAnnales Universitatis Turkuensis A I 536, 2016-04-15)
Metal-ion-mediated base-pairing of nucleic acids has attracted considerable attention during the past decade, since it offers means to expand the genetic code by artificial base-pairs, to create predesigned molecular ...