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The major initial mechanism of acute coronary syndrome (ACS) is the rupture of the atherosclerotic coronary artery plaque. Clinical signs, electrocardiogram and cardiac troponins, as markers of myocardial ischemia or damage, ...

Periprosthetic osteolysis is one of the most significant long-term complications after total ankle arthroplasty (TAA). The exact pathogenesis of osteolysis is unclear. It is a biological process involving many factors, ...

Abstract Early interaction and closeness with a caregiver are important for the development of newborn infants. Postpartum separation between parent and newborn is still common in the hospital care of premature babies. ...

Pertussis or whooping cough is a human respiratory tract infection and a vaccine-preventable disease that is caused by Bordetella pertussis bacteria. Pertussis vaccination has been part of the Finnish national vaccine ...

Alzheimer’s disease (AD) is the most common form of dementia. Characteristic changes in an AD brain are the formation of β-amyloid protein (Aβ) plaques and neurofibrillary tangles, though other alterations in the brain ...

Patients treated in intensive care units require sedation and analgesia. However, sedative drugs also have potential adverse effects, and there is no single ideal sedativeanalgesic drug for these patients. Dexmedetomidine ...

Pneumonia is an important cause of morbidity and hospitalization in children worldwide. Since the development of nucleic acid amplification techniques, rhinovirus (RV) is frequently detected in community-acquired pneumonia ...

Roles of novel biomarkers was studied in progression of cutaneous squamous cell carcinoma (cSCC) as the most common metastatic skin cancer. The incidence of cSCC is increasing worldwide due to lifestyle changes such as ...

Huntington’s disease (HD) is a lethal, dominantly inherited neurodegenerative disorder reported to be unusually rare in Finland. The overall HD prevalence and the proportion of late-onset cases (LOHD) are increasing in ...

Chronic kidney disease (CKD) patients suffer from impaired Health-related Quality of Life (HRQoL). Impaired HRQoL has important implications for their prognosis. Cardiovascular disease (CVD) is common in CKD patients, ...