Viimeksi syötetyt

Aineistot 281-300 / 54666

    • Evolving Patterns of Initial RRMS Treatment in Finland (2013–2022): Insights From a Nationwide Multiple Sclerosis Register 

      Ahvenjärvi, Henrik; Jokinen, Elina; Viitala, Matias; Autio, Henri; Portaankorva, Anne M.; Soilu‐Hänninen, Merja; Krüger, Johanna; Ryytty, Mervi
      <p><strong>Background: </strong>The treatment of relapsing-remitting multiple sclerosis (RRMS) is changing. There are limited data about initial treatment of RRMS in Finland.</p><p><strong>Objective: </strong>Our objectives ...

    • Student teachers’ conceptual understanding of biodiversity loss in a multiple-source learning environment 

      Heikkilä, Mirva; Häkkinen, Miira; Vidbäck, Anni; Mikkilä-Erdmann, Mirjamaija; Sääksjärvi, Ilari E.
      <p> Environmental content is becoming increasingly important in schools, but teachers may have difficulty grasping accurate knowledge. This study investigated how student teachers construct a conceptual understanding of ...

    • Circulating Docosahexaenoic Acid Associates with Insulin-Dependent Skeletal Muscle and Whole Body Glucose Uptake in OlderWomen Born from Normal Weight Mothers 

      Robert M. Badeau; Miikka-Juhani Honka; Marco Bucci; Patricia Iozzo; Johan G. Eriksson; Pirjo Nuutila
      Background: Obesity among pregnant women is common, and their offspring are predisposed to obesity, insulin resistance, and diabetes. The circulating metabolites that are related to insulin resistance and are associated ...

    • X-Ray and Multiwavelength Polarization of Mrk 501 from 2022 to 2023 

      Chen, Chien-Ting J.; Liodakis, Ioannis; Middei, Riccardo; Kim, Dawoon E.; Di Gesu, Laura; Di Marco, Alessandro; Ehlert, Steven R.; Errando, Manel; Negro, Michela; Jorstad, Svetlana G.; Marscher, Alan P.; Wu, Kinwah; Agudo, Iván; Poutanen, Juri; Mizuno, Tsunefumi; Kouch, Pouya M.; Lindfors, Elina; Borman, George A.; Grishina, Tatiana S.; Kopatskaya, Evgenia N.; Larionova, Elena G.; Morozova, Daria A.; Savchenko, Sergey S.; Troitsky, Ivan S.; Troitskaya, Yulia V.; Vasilyev, Andrey A.; Zhovtan, Alexey V.; Aceituno, Francisco José; Bonnoli, Giacomo; Casanova, Víctor; Escudero, Juan; Agís-González, Beatriz; Husillos, César; Otero, Santos Jorge; Sota, Alfredo; Piirola, Vilppu; Myserlis, Ioannis; Angelakis, Emmanouil; Kraus, Alexander; Gurwell, Mark; Keating, Garrett; Rao, Ramprasad; Kang, Sincheol; Lee, Sang-Sung; Kim, Sang-Hyun; Cheong, Whee Yeon; Jeong, Hyeon-Woo; Song, Chanwoo; Berdyugin, Andrei V.; Kagitani, Masato; Kravtsov, Vadim; Nitindala, Anagha P.; Sakanoi, Takeshi; Imazawa, Ryo; Sasada, Mahito; Fukazawa, Yasushi; Kawabata, Koji S.; Uemura, Makoto; Nakaoka, Tatsuya; Akitaya, Hiroshi; Casadio, Carolina; Sievers, Albrecht; Antonelli, Lucio Angelo; Bachetti, Matteo; Baldini, Luca; Baumgartner, Wayne H.; Bellazzini, Ronaldo; Bianchi, Stefano; Bongiorno, Stephen D.; Bonino, Raffaella; Brez, Alessandro; Bucciantini, Niccoló; Capitanio, Fiamma; Castellano, Simone; Cavazzuti, Elisabetta; Ciprini, Stefano; Costa, Enrico; De Rosa, Alessandra; Del Monte, Ettore; Di Lalla, Niccoló; Donnarumma, Immacolata; Doroshenko, Victor; Dovčiak, Michal; Enoto, Teruaki; Evangelista, Yuri; Fabiani, Sergio; Ferrazzoli, Riccardo; Garcia, Javier A.; Gunji, Shuichi; Hayashida, Kiyoshi; Heyl, Jeremy; Iwakiri, Wataru; Kaaret, Philip; Karas, Vladimir; Kislat, Fabian; Kitaguchi, Takao; Kolodziejczak, Jeffery J.; Krawczynski, Henric; La Monaca, Fabio; Latronico, Luca; Maldera, Simone; Manfreda, Alberto; Marin, Frédéric; Marinucci, Andrea; Marshall, Herman L.; Massaro, Francesco; Matt, Giorgio; Mitsuishi, Ikuyuki; Muleri, Fabio; Ng, C.-Y.; O’Dell, Stephen L.; Omodei, Nicola; Oppedisano, Chiara; Papitto, Alessandro; Pavlov, George G.; Peirson, Abel Lawrence; Perri, Matteo; Pesce-Rollins, Melissa; Petrucci, Pierre-Olivier; Pilia, Maura; Possenti, Andrea; Puccetti, Simonetta; Ramsey, Brian D.; Rankin, John; Ratheesh, Ajay; Roberts, Oliver J.; Romani, Roger W.; Sgró, Carmelo; Slane, Patrick; Soffitta, Paolo; Spandre, Gloria; Swartz, Douglas A.; Tamagawa, Toru; Tavecchio, Fabrizio; Taverna, Roberto; Tawara, Yuzuru; Tennant, Allyn F.; Thomas, Nicholas E.; Tombesi, Francesco; Trois, Alessio; Tsygankov, Sergey S.; Turolla, Roberto; Vink, Jacco; Weisskopf, Martin C.; Xie, Fei; Zane, Silvia
      <p>We present multiwavelength polarization measurements of the luminous blazar Mrk 501 over a 14 month period. The 2–8 keV X-ray polarization was measured with the Imaging X-ray Polarimetry Explorer (IXPE) with six 100 ks ...

    • Influence of CYP2D6 phenotype on adherence, adverse effects, and attitudes in aripiprazole and risperidone users 

      Hietala, Elina; Solismaa, Anssi; Lähteenvuo, Markku; Ahola-Olli, Ari V.; Häkkinen, Katja; Suokas, Kimmo; Isometsä, Erkki; Suvisaari, Jaana; Kieseppä, Tuula; Holm, Minna; Tiihonen, Jari; Lönnqvist, Jouko; Hietala, Jarmo; Wegelius, Asko; Lahdensuo, Kaisla; Haaki, Willehard; Kampman, Olli; study SUPER-Finland
      Non-adherence and negative attitudes towards medication are major problems in treating psychotic disorders. Cytochrome P450 2D6 (CYP2D6) contributes to the metabolism of aripiprazole and risperidone, and variations in ...

    • Multimodal prognosis of negative symptom severity in individuals at increased risk of developing psychosis 

      Hauke Daniel J; Schmidt André; Studerus Erich; Andreou Christina; Riecher-Rossler Anita; Radua Joaquin; Kambeitz Joseph; Ruef Anne; Dwyer Dominic B; Kambeitz-Ilankovic Lana; Lichtenstein Theresa; Sanfelici Rachele; Penzel Nora; Haas Shalaila S; Antonucci Linda A; Lalousis Paris A; Chisholm Katharine; Schultze-Lutter Frauke; Ruhrmann Stephan; Hietala Jarmo; Brambilla Paolo; Koutsouleris Nikolaos; Meisenzahl Eva; Pantelis Christos; Rosen Marlene; Salokangas Raimo KR; Upthegrove Rachel; Wood Stephen J; Borgwardt Stefan; Pronia Group
      Negative symptoms occur frequently in individuals at clinical high risk (CHR) for psychosis and contribute to functional impairments. The aim of this study was to predict negative symptom severity in CHR after 9 months. ...

    • Review of Paul A. Roth’s The Philosophical Structure of Historical Explanation (Book review) 

      Virmajoki Veli
      <p>Roth’s book is rich and intense. In a relatively short space, it seeks to locate historical explanations within our general metaphysical and epistemic predicaments. Understanding the argumentative nuances of the book ...

    • Learning with multiple external representations in physics : Concreteness fading versus simultaneous presentation 

      Lichtenberger Andreas; Kokkonen Tommi; Schalk Lennart
      <p></p><p>Multiple external representations (MERs) are useful for teaching complex content in science education. An open question is whether there is an especially effective way to sequence MERs. On the one hand, the ...

    • Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases 

      Kiiskinen Tuomo; Helkkula Pyry; Krebs Kristi; Karjalainen Juha; Saarentaus Elmo; Mars Nina; Lehisto Arto; Zhou Wei; Cordioli Mattia; Jukarainen Sakari; Rämö Joel T.; Mehtonen Juha; Veerapen Kumar; Räsänen Markus; Ruotsalainen Sanni; Maasha Mutaamba; FinnGen; Niiranen Teemu; Tuomi Tiinamaija; Salomaa Veikko; Kurki Mitja; Pirinen Matti; Palotie Aarno; Daly Mark; Ganna Andrea; Havulinna Aki S.; Milani Lili; Ripatti Samuli
      <p>A new analysis of large biobanks uncovers genetic variants associated with longitudinal changes in medication for cardiometabolic diseases and presents polygenic scores of medication-use behavior.Little is known about ...

    • Digitalised higher education: key developments, questions, and concerns 

      Komljenovic, Janja; Birch, Kean; Sellar, Sam; Bergviken Rensfeldt, Annika; Deville, Joe; Eaton, Charlie; Gourlay, Lesley; Hansen, Morten; Kerssens, Niels; Kovalainen, Anne; Nappert, Pier-Luc; Noteboom, Joe; Parcerisa, Lluis; Pardo-Guerra, Juan Pable; Poutanen, Seppo; Robertson, Susan; Tyfield, David; Williamson, Ben
      <p> Higher education is already profoundly digitalised. Students, academics, and university administrators routinely use digital technologies, many of which rely on data, including artificial intelligence. Universities aim ...

    • Responsibility of/in digital transformation 

      Zimmer Markus P.; Järveläinen Jonna; Stahl Bernd C.; Mueller Benjamin
      <p>In this editorial, we chart a path for research on responsible digital transformation (DT). We draw on responsible innovation to provide a framework that can inform the research agenda of the emerging literature of ...

    • Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes 

      Malakoutikhah Morteza; Mahran Randa; Gooran Negin; Masoumi Ahmadreza; Lundell Katri; Liljeblad Arto; Guiley Keelan; Dai Shizhong; Zheng Qinheng; Zhu Lawrence; Shokat Kevan M.; Kopra Kari; Härmä Harri
      <p>Protein properties and interactions have been widely investigated by using external labels. However, the micromolar sensitivity of the current dyes limits their applicability due to the high material consumption and ...

    • Suomi-rockin pinnalla ja pinnan tuntumassa 

      Pertti Grönholm
      Turun Historiallinen Arkisto
      <p>Turkulaisten 1980-luvun pop- ja rock-yhtyeiden historiaa käsittelevä artikeli. </p>

    • Headwater chemistry in subarctic areas with different plant communities (Finnish Lapland) 

      Płaczkowska Eliza; Wasak-Sęk Katarzyna; Żelazny Mirosław; Jelonkiewicz Łukasz; Syvänperä Ilkka; Paavola Riku; Sippola Katja; Partanen Rauni; Leuchner Michael
      <p>The study determines the differences in the chemistry of small headwater streams located in areas with different plant communities in Finnish Lapland. Water samples from 76 catchments with four different plant communities ...

    • Lapsen sairastuminen syöpään aiheuttaa mielenterveysoireita etenkin äidille 

      Vaalavuo Maria; Tahvonen Ossi; Salokangas Henri
      Sylva tutkimus: tietoa & tilastoja

    • Le personnage de la Finlandaise dans le récit Parmi les falaises (1924) de Maria Boretskaïa, au prisme de la tradition littéraire 

      Simonova, Olga
      <p>The article examines the tradition of the representation of Finnish women in Russian literature, which can be divided into two subtypes. The first, created by Russian realist writers, is the <em>Chukhonka</em>, a character ...

    • RAS and PP2A activities converge on epigenetic gene regulation 

      Aakula Anna; Sharma Mukund; Tabaro Francesco; Nätkin Reetta; Kamila Jesse; Honkanen Henrik; Schapira Matthieu; Arrowsmith Cheryl; Nykter Matti; Westermarck Jukka
      RAS-mediated human cell transformation requires inhibition of the tumor suppressor protein phosphatase 2A (PP2A). However, the phosphoprotein targets and cellular processes in which RAS and PP2A activities converge in human ...

    • Jokapaikan lihaskivut, mistä voisi olla kyse? 

      Mali Markku; Kauppi Markku
      <p>Myalgiat eli lihaskivut ovat epäspesifinen ja yleinen vaiva yleislääkärin vastaanotolla. Lähes kaikki kokevat jossain vaiheessa elämäänsä lihasarkuutta ja -kipua.</p><p>Suurimmalta osalta tapaukset ovat hyvänlaatuisia ...

    • Nurse managers’ early intervention in nurses’ professional conduct: A document analysis 

      Papinaho Oili; Häggman-Laitila Arja; Kangasniemi Mari
      Nurses’ professional conduct and work-related well-being are crucial for providing high-quality, safe patient care. Previous knowledge about nurse managers’ early interventions in nurses’ professional conduct is scarce. ...

    • Documentation and preservation of German WWII airfields in Finland 

      Väisänen Teemu; Pancíř Tomáš; Pauley Charles
      <p>In this paper, we discuss the heritage and research potential of Second World War airfields in Finland. Our focus is on the airfields used by the German Luftwaffe during the Continuation War and Lapland War. The German ...