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Aineistot 11-20 / 227
Regulation of Schwann cells and osteoclasts with an emphasis on NF1-deficient cells
(Turun yliopisto, 2019-06-08)
ABSTRACT
Neurofibromatosis type 1 (NF1) is a dominantly inherited cancer predisposition syndrome, which affects one in 2000 individuals worldwide. NF1 exhibits a variety of clinical symptoms. Neurofibromas, the hallmarks ...
Wood biochemicals for the protection of health. Focus on hemicellulose, stilbenoids and lignans
(Annales Universitatis Turkuensis D 1173Turun yliopisto, 2015-05-13)
Trees produce an enormous amount of compounds that are still scantly utilized.However, the results obtained from structurally similar biochemicals suggest that wood-derived compounds could be used for the protection of ...
Modulation of Signaling Molecules by Human Leucocyte Antigen B27; Special Reference to STAT1
(Annales Universitatis Turkuensis D 1144Turun yliopisto, 2014-11-21)
Reactive arthritis (ReA) is an inflammatory joint disease, which belongs to the group of Spondyloarthritis (SpA). It may occur after infections with certain gram-negative bacteria such as Salmonella and Yersinia. SpAs are ...
PLVAP as the gatekeeper of endothelial cell permeability and leukocyte migration
(Turun yliopisto, 2019-10-11)
Endothelial cells (EC) line the lymphatic and vascular vessels of the body, forming a barrier between the lumen and surrounding tissue. ECs actively coordinate the exchange of migrating cells, fluids and molecules thus ...
Immobilization of Burkholderia cepacia Lipase: Kinetic Resolution in Organic Solvents, Ionic Liquids and in Their Mixtures
(Annales Universitatis Turkuensis A D 977Turun yliopisto, 2011-09-23)
<b>Immobilization of <i>Burkholderia cepacia</i> Lipase: Kinetic Resolution in Organic Solvents, Ionic Liquids and in Their Mixtures</b>
Biocatalysis opens the door to green and sustainable processes in synthetic ...
Upconverting diagnostics: Multiplex assays utilizing upconversion luminescence technology
(Annales Universitatis Turkuensis D 1117Turun yliopisto, 2014-06-13)
Conventional diagnostics tests and technologies typically allow only a single analysis and result per test. The aim of this study was to propose robust and multiplex array-inwell test platforms based on oligonucleotide and ...
The effect of training background on oxidized lipoprotein lipids and antioxidant capacity in athletes and keep-fit runners
(Turun yliopisto, 2018-12-07)
Background: High-intensity acute exercise is known to induce oxidative stress and may lead to harmful oxidation of lipids, and protein and DNA damage. On the other hand, exercise is known to positively influence risk factors ...
A Systems Biology Analysis of PP2A Functions in Cancer Cells
(Annales Universitatis Turkuensis D 1264Turun yliopisto, 2017-01-20)
Cancer is characterized by aberrant activation of phosphorylation signalling cascades. However, despite the critical role of phosphatases in protein phosphorylation, their contribution to cancer cell signalling is only ...
Studies on the pathogenesis and laboratory diagnosis of Lyme borreliosis
(Turun yliopisto, 2019-01-18)
Lyme borreliosis, the most common tick-borne disease in the northern hemisphere, is caused by Borrelia burgdorferi sensu lato spirochetes (later Borrelia). They can infect humans through bites of infected Ixodes ticks. If ...
Lipase and omega-transaminase catalysis in preparation of alcohol and amine enantiomers
(Annales Universitatis Turkuensis D 1126Turun yliopisto, 2014-09-12)
Enantiopure intermediates are of high value in drug synthesis. Biocatalysis alone or combined with chemical synthesis provides powerful tools to access enantiopure compounds. In biocatalysis, chemo-, regio- and enantioselectivity ...