Viimeksi syötetyt Väitöskirjat
Aineistot 181-200 / 2960
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Sedentary behavior, physical activity, and energy metabolism in metabolic syndrome : with special reference to insulin sensitivity and metabolic flexibility
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1808 (Turun yliopisto, 28.09.2024)ABSTRACT This study investigated the relationships between physical activity behaviors and energy metabolism in 64 middle-aged, sedentary adults with metabolic syndrome. Associations were examined cross-sectionally, and ... -
ERBB4 as a potential therapeutic target in cancer
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1812 (Turun yliopisto, 04.10.2024)ABSTRACT EGFR/ERBB/HER family of receptor tyrosine kinases are frequently mutated, and hence, aberrantly active in cancer. Currently, numerous ERBB-targeted therapies are used to treat various types of cancer, using ... -
Surveillance of Antimicrobial Resistant Bacteria in Africa and Namibia
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1816 (Turun yliopisto, 27.09.2024)ABSTRACT Sub-Saharan Africa faces a growing antimicrobial resistance (AMR) threat. Antimicrobial resistant bacterial organisms pose a serious problem to human infection treatment, particularly urinary tract infections ... -
The role of HSD17B3 in male development and health: Disruption of testosterone production and its effects
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1813 (Turun yliopisto, 04.10.2024)ABSTRACT Hydroxysteroid (17β) dehydrogenase type 3 (HSD17B3) is known to be the primary enzyme converting androstenedione (A) to testosterone (T) in human and mouse testes. It is therefore important for male development ... -
Psychiatric problems during childhood and adolescence and later labour market marginalisation
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1818 (Turun yliopisto, 27.09.2024)ABSTRACT Low educational attainment and problems with employment are common among people with psychiatric disorders. Psychiatric disorders often start in childhood or adolescence. The main goal of this thesis was to ... -
Magnetic resonance imaging in paediatric spinal trauma – retrospective analysis of feasibility, safety, and diagnostic value in the emergency department
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1801 (Turun yliopisto, 18.10.2024)Paediatric spinal trauma is a relatively uncommon but challenging entity in the emergency department. Despite the algorithms aiming to exclude spinal trauma based on symptoms and physical examination, medical imaging is ... -
Integrin mediated regulation of apicobasal polarity, cell states and cancer progression
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 44 (Turun yliopisto, 23.09.2024)Integrins regulate cell adhesion, migration and architecture which play a role both in development of healthy tissues and disease. While integrins have been widely studied amongst models, the way their availability acts ... -
Novel bone SPECT-CT methods – Optimization and validation for imaging bone metastases
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1807 (Turun yliopisto, 27.09.2024)Bone single-photon emission computed tomography (SPECT) combined with X-ray computed tomography (SPECT-CT) is expected to replace planar bone scintigraphy (BS) as the routine method for imaging bone metastases. In preparation ... -
Child brain development: exploring prenatal impacts and emotional perception through advanced neuroimaging – Findings from the FinnBrain Birth Cohort MRI Study
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1815 (Turun yliopisto, 13.09.2024)The amygdala, a key player in emotional processing, undergoes rapid growth and development prenatally and in infancy. Environmental factors, such as prenatal maternal depressive symptoms, can alter the structure of the ... -
Bacterial meningitis - Incidence, Etiology, Predisposing Factors and Outcome
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1810 (Turun yliopisto, 20.09.2024)Bacterial meningitis (BM) is a severe infectious disease, which causes significant morbidity and mortality up to 30%. BM can be classified into community-acquired or nosocomial form. Post-neurosurgical meningitis (PNM), a ... -
Vascularised lymph node transfer and lymphatic growth factors in the treatment of lymphedema
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1805 (Turun yliopisto, 20.09.2024)Lymphedema is a progressive disease that can significantly deteriorate the quality of life of patients if not treated appropriately. The conventional treatment for lymphedema has been conservative, with the continuous use ... -
Monista näkökulmista tautiluokkakeskeisyyteen: Masennuksen määrittyminen Turun yliopiston opiskelijoiden, väitöskirjatutkijoiden ja erikoistuvien lääkärien käsityksissä vuosina 1980–1995
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis B: Humaniora : 677 (Turun yliopisto, 14.09.2024)Väitöskirjassa tutkitaan, millaisia ryhmäkohtaisia masennuskäsityksiä Turun yliopiston psykologian laitoksen ja lääketieteellisen tiedekunnan opiskelijoilla, erikoistuvilla lääkäreillä ja väitöskirjatutkijoilla oli vuosina ... -
Kolonialismia ilman siirtomaita?: Kulttuurinen kolonialismi ja ”rotu” suomalaisessa lasten- ja nuortenkirjallisuudessa ja lapsille suunnatuissa lehdissä, 1900–1960
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis B: Humaniora : 676 (Turun yliopisto, 13.09.2024)Tässä artikkeliväitöskirjassa tutkitaan kulttuurisen kolonialismin ilmenemistä suomalaisessa lasten- ja nuortenkirjallisuudessa sekä lapsille suunnatuissa lehdissä 1900-luvun alusta 1960-luvun alkuun. Tutkimus tarkastelee ... -
FDI and technological advancement in the Global South Perspectives on the emergence of Medellín as an investment hub
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser E: Oeconomica : 120 (Turun yliopisto. Turun kauppakorkeakoulu, 27.09.2024)Foreign direct investment (FDI) flows are increasingly global, diverse, and knowledge intensive. However, existing research predominantly focuses on those involving advanced and leading emerging economies and large ... -
Functional disulfide macrocycles from dynamic combinatorial libraries
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser AI: Astronomica - Chemica - Physica – Mathematica : 723 (Turun yliopisto, 09.09.2024)Dynamic combinatorial chemistry (DCC) is an ideal tool used to create complex chemical systems, where a variety of components are produced in a combinatorial way by linking building blocks through reversible chemical bonds ... -
Sikojen eletyt tilat ja paikat. Sikalat, siankasvatus ja sianhoito 1900-luvun alun Suomessa
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis B: Humaniora : 674 (Turun yliopisto, 18.10.2024)Tutkin väitöskirjassani siankasvatukseen ja sianjalostukseen käytettyjen sikojen elettyä elämää Suomessa 1900-luvun alussa. Kysyn tutkimuksessani, miten siitossikojen tilat ja hoidon käytännöt muotoutuivat 1900-luvun alusta ... -
Algoritmiset haitat: Tekoälyn riskit ja sääntelyn haasteet kiihtyvässä yhteiskunnassa
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis B: Humaniora : 675 (Turun yliopisto, 12.09.2024)Tekoäly on levittänyt vaikutustaan yhä laajemmin yhteiskunnan eri osa-alueille, ja algoritmisen transformaation vauhti näyttäisi vain kiihtyvän. Algoritmiset teknologiat ovat kietoutuneet erottamattomaksi osaksi yhteiskuntaa, ... -
Perceived school safety, help-seeking for mental health problems, and cyberbullying related to suicide attempt among adolescents in 13 Asian and European countries
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1806 (Turun yliopisto, 30.08.2024)ABSTRACT Cross-national research on the mental health of adolescents is essential for understanding the unique challenges they face, identifying trends and risk factors, and ultimately promoting positive mental health ... -
P16 and xCT as Biomarkers in Oropharyngeal Squamous Cell Carcinoma and Beyond
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1802 (Turun yliopisto, 06.09.2024)Current therapy stratification of head and neck squamous cell carcinomas (HNSCCs) is based on clinical features. This approach often fails to capture the enormous biologic heterogeneity of the disease entity. Therefore, ... -
Radiolabeling of spherical oligonucleotides for targeted and pretargeted PET imaging : Biological evaluation of structural effects by using a tetrazine [¹⁸F]fluoroglycoconjugate
Turun yliopiston julkaisuja. Sarja A I, Chemica - Physica – Mathematica : 179 (Turun yliopisto, 13.09.2024)Positron emission tomography (PET) is a sensitive and non-invasive molecular imaging modality with various applications, including drug discovery and the development of novel therapeutics evaluation at an early stage. ...