Viimeksi syötetyt Väitöskirjat

Aineistot 781-800 / 3082

    • Ideation for future cruise ships: Collaborative interorganisational foresight in cruise ship concept ideation 

      Jokinen, Leena
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser E: Oeconomica : 86 (Turun yliopisto. Turun kauppakorkeakoulu, 25.03.2022)
      The thesis addresses two main questions: how to capture the dynamics of futuresfocused thinking and acting in everyday work contexts and how futures studies (FS) methodology can be developed for analysing how social relations ...

    • Pathogenesis of LMNA-related dilated cardiomyopathy 

      Virtanen, Laura
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1609 (Turun yliopisto, 04.03.2022)
      Dilated cardiomyopathy (DCM) is a progressive myocardial disease that leads to dilatation of cardiac ventricles, reduced contractile force, and a high risk of sudden cardiac death. The second most common gene mutated in ...

    • Photoprotection and genetic autonomy of plastids in photosynthetic sea slugs 

      Havurinne, Vesa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 666 (Turun yliopisto, 11.03.2022)
      Certain sea slugs “steal” the photosynthetic cellular organelles, the plastids, from their prey algae and incorporate them, still functional, inside their own cells. These animals can then remain photosynthetic for months. ...

    • Fluorescent and 19F NMR probes for metal-mediated base pairing 

      Aro-Heinilä, Asmo
      Turun yliopiston julkaisuja -Annales Universitatis Turkuensis AI: Astronomica - Chemica- Phsysica : 664 (Turun yliopisto, 04.03.2022)
      Research on metal-mediated base pairing has proceeded rapidly during the last decades, and metal-mediated base pairs have become one noteworthy option for developing new DNA-based biological or nanotechnological applications. ...

    • Balance disturbance and orthostatic hypotension as risk factors for falls among older adults 

      Hohtari-Kivimäki, Ulla
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 2343-3213 (Turun yliopisto, 25.02.2022)
      Falls present common serious clinical problems among older adults. To detect older adults with a high risk to fall, there is a need to develop clinically usable tools. For clinicians, balance is an important aspect of fall ...

    • Reducing dislocations of total hip arthroplasty 

      Karvonen, Mikko
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1610 (Turun yliopisto, 04.03.2022)
      Dislocation is one of the most common complications following total hip arthroplasty (THA). There are several concepts that can be used to reduce the number of dislocations, including elevated liners, larger femoral heads, ...

    • Safety and quality of surgical treatment of early onset scoliosis 

      Saarinen, Antti J.
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1608 (Turun yliopisto, 11.02.2022)
      Early onset scoliosis (EOS) is defined as abnormal lateral curvature of the spine diagnosed before the age of 10. Untreated EOS is prone to progression and may complicate the normal development of the thoracic cavity and ...

    • Surgery for degenerative and rheumatoid cervical spine disease in Finland 

      Kotkansalo, Anna
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1596 (Turun yliopisto, 11.02.2022)
      The operative indications for degenerative cervical spine disease (DCSD) are not explicit and the operative technique is decided on a personalized basis. The rate of surgery for DCSD has risen in the United States and the ...

    • Enhanced label-free discovery proteomics through improved data analysis and knowledge enrichment 

      Välikangas, Tommi
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. F: Technica - Informatica : 8 (Turun yliopisto, 11.02.2022)
      Mass spectrometry (MS)-based proteomics has evolved into an important tool applied in fundamental biological research as well as biomedicine and medical research. The rapid developments of technology have required the ...

    • Bioactive compounds in oats and gut health 

      Laito, Salla
      Doctoral Theses in Food Sciences at The University of Turku : 85 (Turun yliopisto, 04.02.2022)
      Recently, the nutritional advantages of oats have been acknowledged worldwide and several novel oat-based products have entered the market. Health claims on the cholesterol- and postprandial glycemia-lowering effects of ...

    • The construct of the ethical activity profile of nurse managers – effectiveness of the Ethics Quarter e-learning intervention 

      Laukkanen, Laura
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1605 (Turun yliopisto, 04.02.2022)
      Nurse managers’ ethical activities have a positive impact on personnel, the quality of patient care and overall organizational success. The aim of this two-phase study was to create the theoretical construct of the ethical ...

    • Machine learning and computational methods to identify molecular and clinical markers for complex diseases – case studies in cancer and obesity 

      Seyednasrollah, Fatemeh
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Mathematica : 663 (Turun yliopisto, 04.02.2022)
      In biomedical research, applied machine learning and bioinformatics are the essential disciplines heavily involved in translating data-driven findings into medical practice. This task is especially accomplished by developing ...

    • Hormone replacement therapy among Finnish menopausal women around millennium with special attention on the psychosocial background 

      Jalava-Broman, Jaana
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1599 (Turun yliopisto, 28.01.2022)
      Women today can live up to half of their lives postmenopausal. That is why the treatment of climacteric symptoms has become increasingly important. Estrogen effectively alleviates climacteric symptoms and thus improves the ...

    • Optimizing text mining methods for improving biomedical natural language processing 

      Mehryary, Farrokh
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. F: Technica - Informatica : 9 (Turun yliopisto, 04.02.2022)
      The overwhelming amount and the increasing rate of publication in the biomedical domain make it difficult for life sciences researchers to acquire and maintain all information that is necessary for their research. Pubmed ...

    • Novel prognostic factors for advanced melanoma and localized renal cell carcinoma 

      Mattila, Kalle E.
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1607 (Turun yliopisto, 28.01.2022)
      This study aimed to evaluate prognostic and predictive factors in melanoma and renal cell carcinoma to tailor optimal treatment and follow-up for cancer patients. Chemotherapy was the standard treatment for advanced ...

    • Metabolic pathway engineering of actinomycetes for novel antibiotics discovery 

      Baral, Bikash
      Turun yliopiston julkaisuja-Annales Universitatis Turkuensis AI: Astronomica - Chemica- Phsysica : 662 (Turun yliopisto, 21.01.2022)
      Microbes harbouring a profound wealth of chemical space have instigated tremendous attention for developing crucial therapeutic drugs. The genes encoding the enzymes responsible for synthesizing these specialized metabolites ...

    • Is substance use of any substance? Study on substance use and mental health on Russian, Somali and Kurdish origin populations in Finland 

      Salama, Essi
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1601 (Turun yliopisto, 04.02.2022)
      To date, our knowledge on substance use in migrated populations in their host countries is scarce. In addition, associations between discrimination and substance use have been rarely investigated in the European context. The ...

    • Essays on labour market policy evaluation 

      Vehkasalo, Ville
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser E: Oeconomica : 85 (Turun yliopisto. Turun kauppakorkeakoulu, 28.01.2022)
      This thesis presents three previously published case studies and a new summary article, with the overall aim of improving our understanding of the use of natural experiments in studying causal relationships in social ...

    • Data-independent acquisition mass spectrometry for human gut microbiota metaproteome analysis 

      Pietilä, Sami
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1603 (Turun yliopisto, 13.01.2022)
      Human digestive tract microbiota is a diverse community of microorganisms having complex interactions between microbes and the human host. Observing the functions carried out by microbes is essential for gaining understanding ...

    • Temporal trends and outcomes in aortic and mitral valve surgery in Finland 

      Myllykangas, Monna
      Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1604 (Turun yliopisto, 21.01.2022)
      Aortic valve surgery is the most common type of heart valve surgery in western countries. The main causes for aortic valve surgery are aortic valve stenosis and regurgitation. Mitral valve regurgitation is the most common ...