Viimeksi syötetyt
Aineistot 11761-11780 / 46616
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The Mediating Role of Resilience and Self-Esteem Between Life Events and Coping Styles Among Rural Left-Behind Adolescents in China: A Cross-Sectional Study
Objective: This study aims to explore the association between life events and coping styles, and how resilience and self-esteem mediate the association.Methods: A cross-sectional study was conducted among 981 left-behind ... -
Exploring unsupervised query paraphrasing to identify relevant search phrases for a literature review
<p>Literature databases have multifaceted search options, but emerging research areas do not have an established terminology and therefore it is difficult to find relevant literature when conducting a review. This study ... -
Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease
<p>Introduction: ORM-12741 is a novel selective antagonist of alpha-2C adrenoceptors. This trial evaluated the safety and efficacy of ORM-12741 in patients with Alzheimer’s disease (AD). Methods: A randomized, double-blind, ... -
Tuning adhesion forces between functionalized gold colloidal nanoparticles and silicon AFM tips: Role of ligands and capillary forces
<p>Adhesion forces between functionalized gold colloidal nanoparticles (Au NPs) and scanning probe microscope silicon tips were experimentally investigated by atomic force microscopy (AFM) equipped with PeakForce QNM ... -
New and poorly known Palaearctic fungus gnats (Diptera, Sciaroidea)
<p>Background<br />Fungus gnats (Sciaroidea) are a globally species rich group of lower Diptera. In Europe, Fennoscandian peninsula in particular holds a notable diversity, ca. 1000 species, of which 10 % are still unnamed. ... -
Finnish DMP evaluation guidance
Tuuli working group<p>This guide gives some general tips for evaluators. It can be used when evaluating DMP by students, peer reviewing or when evaluation is conducted by a data steward. The working group hopes you develop the guidance further ... -
Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma
<p>Mutations in Fanconi Anemia or Homologous Recombination (FA/HR) genes can cause DNA repair defects and could therefore impact cancer treatment response and patient outcome. Their functional impact and clinical relevance ... -
Efficient hyperparameter tuning for kernel ridge regression with Bayesian optimization
Machine learning methods usually depend on internal parameters-so called hyperparameters-that need to be optimized for best performance. Such optimization poses a burden on machine learning practitioners, requiring expert ... -
Debates on European Integration in the Finnish Parliament (Eduskunta) 1990-2020
CEUR workshop proceedings<p>In this article I analyse parliamentary debates of the Finnish Parliament (Eduskunta) on European integration from 1990 to 2020. Finland joined the European Union (EU) in 1995, but Finland’s integration history dates ... -
Tandem-Mass-Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses under Diseased Condition
The analysis of nanoparticles' biocompatibility and immunogenicity is mostly performed under a healthy condition. However, more clinically relevant evaluation conducted under pathological condition is less known. Here, the ... -
Interaction of storage medium and silver diamine fluoride on demineralized dentin
<div><b>Objective:</b> The effects of saliva on demineralized dentin and silver diamine fluoride (SDF) were investigated in vitro.</div><div><b>Methods:</b> Dentin samples stored in deionized water (DIW), buffer solution ... -
Outbreak of invasive pneumococcal disease among shipyard workers, Turku, Finland, May to November 2019
<p>We report an outbreak of invasive pneumococcal disease and pneumococcal pneumonia among shipyard workers, in Turku, Southwest Finland. In total, 31 confirmed and six probable cases were identified between 3 May and 28 ... -
Modeling genetic heterogeneity of drug response and resistance in cancer
<p>Heterogeneity in tumors is recognized as a key contributor to drug resistance and spread of advanced disease, but deep characterization of genetic variation within tumors has only recently been quantifiable with ... -
Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo
<b>Background: </b>Prostate cancer (PC) metastasizes to the skeleton forming predominantly sclerotic lesions, and there is currently no cure for bone metastatic disease. The transcription factor signal transducer and ... -
Participation in Benefit-Sharing Arrangements in the Komi Republic
<p>The oil industry is vital for the economy of the Komi Republic in Russia. It also benefits the municipalities<br />near oil production sites in terms of benefit-sharing agreements between oil companies and local ...
