Viimeksi syötetyt Väitöskirjat
Aineistot 2701-2720 / 3084
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Early nutritional determinants in cardio-metabolic programming – A prospective randomized controlled dietary intervention study
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 944 (Turun yliopisto, 07.01.2011)Western societies have been faced with the fact that overweight, impaired glucose regulation and elevated blood pressure are already prevalent in pediatric populations. This will inevitably mean an increase in later ... -
Novel Players in the Integrin Signaling Orchestra: TCPTP and MDGI
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 943 (Turun yliopisto, 07.01.2011)Metastases are the major cause of cancer deaths. Tumor cell dissemination from the primary tumor utilizes dysregulated cellular adhesion and upregulated proteolytic degradation of the extracellular matrix for progeny ... -
The geographic mosaic of coevolving plant-herbivore interactions: genetic variation, local adaptation and plant secondary chemistry
Turun yliopiston julkaisuja. Sarja AII, Biologica - Geographica – Geologica : 258 (Turun yliopisto, 17.12.2010) -
Regulation of B Cell Gene Expression and Function by Ikaros, Helios and Bcl6
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 935 (Turun yliopisto, 17.12.2010)B lymphocytes constitute a key branch of adaptive immunity by providing specificity to recognize a vast variety of antigens by B cell antigen receptors (BCR) and secreted antibodies. Antigen recognition activates the cells ... -
Targeted Therapy Possibilities for Metastatic Melanoma
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 940 (Turun yliopisto, 10.12.2010)The incidence of malignant melanoma of the skin has been steadily rising worldwide during the past decades. Most early detected primary tumors can be removed surgically and the prognosis is good. However, at the same time ... -
Factors Regulating Chondrogenic Differentiation
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 938 (Turun yliopisto, 10.12.2010)Chondrogenesis is a co-ordinated differentiation process in which mesenchymal cells condensate, differentiate into chondrocytes and begin to secrete molecules that form the extracellular matrix. It is regulated in a ... -
Berry polyphenol absorption and the effect of northern berries on metabolism, ectopic fat accumulation, and associated diseases
(Turun yliopisto, 03.12.2010)The prevalence of obesity and type 2 diabetes has increased at an alarming rate in developed countries. It seems in the light of current knowledge that metabolic syndrome may not develop at all without NAFLD, and NAFLD is ... -
Natural history of celiac disease-associated antibodies and progression to overt disease in children at increased genetic risk
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 936 (Turun yliopisto, 10.12.2010)Background: Celiac disease is a lifelong, gluten-sensitive, autoimmune-mediated chronic enteropathy, tightly associated with risk alleles at the HLA class II genes. Aims: This study was carried out as a part of the ... -
Bisphosphonate Inhibition of Prostate Cancer Cell Invasion, Migration and Cytoskeletal Organization
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 939 (Turun yliopisto, 11.12.2010)Metastatic bone lesions are commonly associated with prostate cancer affecting approximately 60-80% of the patients. The progression of prostate cancer into an advanced stage is a complex process and its molecular mechanisms ... -
Interactions between Polyunsaturated Fatty Acids and Probiotics
(Turun yliopisto, 08.12.2010)The prevalence of inflammatory based diseases has increased in industrialized countries over the last decades. For allergic diseases, two primary hypotheses have been proposed to explain this phenomenon, namely the hygiene ... -
Promoting Programming Learning. Engagement, Automatic Assessment with Immediate Feedback in Visualizations
TUCS Dissertations : 131 (Turku Centre for Computer Science, 11.12.2010)The skill of programming is a key asset for every computer science student. Many studies have shown that this is a hard skill to learn and the outcomes of programming courses have often been substandard. Thus, a range of ... -
Targeting Adenoviral Gene Therapy Vectors to Head and Neck Squamous Cell Carcinoma and Heart
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 937 (Turun yliopisto, 03.12.2010)Gene therapy aims to treat diseases by introducing genetic material to the diseased tissue. For cancer treatment it is important to destroy cancerous cells; this can be achieved by introducing a gene, which induces cell ... -
Anchor or Accelerate – A Study on Cancer Cell Adhesion and Motility
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 934 (Turun yliopisto, 26.11.2010)Cell migration and adhesion to the extracellular matrix (ECM) are crucial in many biological and pathological processes such as morphogenesis, tissue repair, inflammatory responses, survival, and cancer. Cell-matrix adhesion ... -
The Role of Cytochrome P450 3A Inducers and Inhibitors in the Metabolism and the Effects of Oxycodone
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 932 (Turun yliopisto, 04.12.2010)Oxycodone is an opioid used in the treatment of moderate or severe pain. It is principally metabolized in the liver by cytochrome P450 3A (CYP3A) enzymes whereas approximately 10% is metabolized by CYP2D6. Little is known ... -
Viral and cellular modulation of virus-induced apoptosis in experimental infection models
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 930 (Turun yliopisto, 10.12.2010)The aim of this study was to investigate herpes simplex virus type 1 (HSV-1)- and measles virus (MV)-induced cell death. HSV-1 with deletion in genes encoding infected cell protein (ICP)4 and protein kinase Us3 (d120) ... -
Functional characterization of proteins required for mitotic progression and the spindle assembly checkpoint
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 933 (Turun yliopisto, 03.12.2010)During mitotic cell division, the genetic material packed into chromosomes is divided equally between two daughter cells. Before the separation of the two copies of a chromosome (sister chromatids), each chromosome has to ... -
Cultural and textual properties in the translation and interpretation of allusions. An analysis of allusions in Dorothy L. Sayers’ detective novels translated into Finnish in the 1940s and the 1980s
Turun yliopiston julkaisuja. Sarja B, Humaniora : 330 (Turun yliopisto, 10.12.2010)<b>Kulttuuriset ja tekstuaaliset tekijät alluusioiden kääntämisessä ja tulkinnassa. Alluusiot Dorothy L. Sayersin 1940- ja 1980-luvuilla suomennetuissa salapoliisiromaaneissa</b> Väitöskirja käsittelee alluusioiden ... -
Studies on the Multifaceted Interaction of Atoms and an Electromagnetic Field
Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 415 (Turun yliopisto, 27.11.2010)In this Thesis the interaction of an electromagnetic field and matter is studied from various aspects in the general framework of cold atoms. Our subjects cover a wide spectrum of phenomena ranging from semiclassical ... -
Romanssien ja runouden aikakausi. Thomas Warton keskiaikaa määrittelemässä 1750–1790
Turun yliopiston julkaisuja. Sarja C, Scripta lingua Fennica edita : 305 (Turun yliopisto, 27.11.2010)Tutkimukseni käsittelee keskiajan nousua historian tärkeäksi periodiksi 1700-luvun Englannissa näkökulmanaan Thomas Wartonin (1726–1790) kirjoitukset. Warton oli Oxfordin yliopistossa toiminut oppinut antikvaari. Wartonin ... -
Improving Quality of Life of Patients With Schizophrenia In Acute Psychiatric Wards
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 931 (Turun yliopisto, 26.11.2010)The overall goal of this study was to identify means by which the quality of life (QoL) of patients with schizophrenia could be improved in acute psychiatric wards. First, subjective QoL of patients (n=35) was explored. ...
